Obesity-related liver disease is projected to become the leading indication for liver transplantation (LT) in the next decade. The number of obese transplant recipients is increasing; 39% of transplant recipients had class I (body mass index [BMI] ≥30 kg/m 2 ) obesity in 2017, compared to 21% in 2007. 1 Obese adults undergoing LT have a higher risk of perioperative morbidity, and long-term outcomes including allograft function may be affected by obesity-related complications. 2,3 Weight gain is an important burden in the posttransplant period. 1,4 In those adults undergoing LT for nonalcoholic fatty liver disease (NAFLD), recurrent NAFLD develops in 30%-60% within 5 years after LT. 5 Despite the increasing prevalence of obesity in LT, there is no well-established management algorithm for the obese LT candidate.
Weight reduction through lifestyle modifications is often difficult