Endoscopic microsuture repair of vocal fold defects

Woo, Peak; Casper, Janina K.; Griffin, Barbara; Colton, Raymond H.; Brewer, David

doi:10.1016/s0892-1997(05)80242-5

Cited by 37 publications

(41 citation statements)

References 6 publications

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“…If there is loss of epithelium or dislodgement of the microflap, then healing can occur by secondary intention. In this case granulation tissue formation and epithelial migration occur (Woo 1995), and there is correspondingly more scar tissue formation Voice rest is usually prescribed after surgery (Ishikawa and Thibeault 2010), but even with a totally compliant patient, apposition of epithelial flaps edges can be difficult to maintain. Thus various methods like micro-sutures and fibrin glue (Bleach, Milford et al 1997;Flock 2005;Kitahara, Masuda et al 2005;Finck, Harmegnies et al 2010;Skodacek, Arnold et al 2011) have been used to improve wound closure and minimize scar tissue formation.…”

Section: Wound Closurementioning

confidence: 99%

“…The use of microsutures in vocal fold wound closure was proposed by Woo et al in 1995, hypothesizing that microsutures would allow precise positioning of wound edges and maintenance of the approximation (Woo 1995). This would reduce exposure of the wound site and permit primary healing to occur.…”

Section: Microsuturesmentioning

confidence: 99%

“…Conventionally, these micro-flaps are left to epithelialize without formal closure, which can result in healing by secondary intention and increased scar tissue formation (Woo 1995;Thekdi and Rosen 2002). Scar tissue in the lamina propria of the vocal fold affects its visco-elastic and vibrational properties (Bless and Welham 2010), disrupting the mucosal wave and often manifesting as hoarseness and a reduction in the phonatory capabilities of the patient (Thibeault, Gray et al 2002).…”

Section: Introductionmentioning

confidence: 99%

“…Scar tissue in the lamina propria of the vocal fold affects its visco-elastic and vibrational properties (Bless and Welham 2010), disrupting the mucosal wave and often manifesting as hoarseness and a reduction in the phonatory capabilities of the patient (Thibeault, Gray et al 2002). Since the precision of epithelial approximation accomplished during the surgical procedure and retained during the healing process affects the amount of scar tissue formation (Woo 1995), wound closure is of particular interest in voice microsurgery.…”

Section: Introductionmentioning

confidence: 99%

“…Extensive work has focused on improving wound closure methods to minimize scar tissue formation, ranging from micro-suturing which allows for primary healing (Woo 1995;Tsuji, Nita et al 2009), to the use of tissue adhesives like fibrin glue (Bleach, Milford et al 1997;Flock 2005;Kitahara, Masuda et al 2005;Finck, Harmegnies et al 2010;Skodacek, Arnold et al 2011), and the use of chemical agents (Campagnolo, Tsuji et al 2010) like Mitomycin-C (Branski, Verdolini et al 2006;Fonseca, Malafaia et al 2010) or stem cells (Hong, Lee et al) to enhance the healing process of vocal fold wounds. However, various challenges faced in the execution of voice microsurgery add to the complexity of wound closure.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Investigation of Experimental Wound Closure Techniques in Voice Microsurgery

Chng¹,

Lau²,

Choo³

et al. 2012

Otolaryngology

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Section: Wound Closurementioning

confidence: 99%

Section: Microsuturesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Investigation of Experimental Wound Closure Techniques in Voice Microsurgery

Chng¹,

Lau²,

Choo³

et al. 2012

Otolaryngology

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Sample‐based approaches to decision making problems under uncertainty

Lee¹,

Yang²,

Prasad³

et al. 2011

Can J Chem Eng

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Decision making under uncertainty is becoming more important in process industries as optimisation is applied to novel applications as well as plant‐wide and enterprise optimisation. Among the standard stochastic optimisation techniques are stochastic programming and dynamic programming. It is difficult to use these techniques for practical applications due to unwieldy computational requirements, arising from a large number of uncertain parameters and state variables, respectively. In this paper, we present sample‐based techniques for ameliorating the computational difficulties. Application studies involving catalyst design and real‐time optimisation point to the promising potentials of the sample‐based techniques. © 2011 Canadian Society for Chemical Engineering

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Modeling and simulation of material degradation in biodegradable wound closure devices

et al. 2014

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Biodegradable materials have been used as wound closure materials. It is important for these materials to enhance wound healing when the wound is vulnerable, and maintain wound closure until the wound is heal. This article studies the degradation process of bioresorbable magnesium micro-clips for wound closure in voice/laryngeal microsurgery. A novel computational approach is proposed to model degradation of the biodegradable micro-clips. The degradation process that considers both material and geometry of the device as well as its deployment is modeled as an energy minimization problem that is iteratively solved using active contour and incremental finite element methods. Strain energy of the micro-clip during degradation is calculated with the stretching and bending functions in the active contour formulation. The degradation rate is computed from strain energy using a transformation formulation. By relating strain energy to material degradation, the degradation rates and geometries of the micro-clip during degradation can be represented using a simulated degradation map. Computer simulation of the degradation of the micro-clip presented in the study is validated by in vivo and in vitro experiments.

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Endoscopic microsuture repair of vocal fold defects

Cited by 37 publications

References 6 publications

Investigation of Experimental Wound Closure Techniques in Voice Microsurgery

Investigation of Experimental Wound Closure Techniques in Voice Microsurgery

Sample‐based approaches to decision making problems under uncertainty

Modeling and simulation of material degradation in biodegradable wound closure devices

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