1989
DOI: 10.1007/bf01538087
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Endoscopic laser therapy for duodenal villous adenoma

Abstract: A 72-year-old woman had a 20-mm supraampullary villoglandular adenoma with a focal carcinoma in situ. The neurological status of the patient did not allow any major surgical procedure. Therefore laser therapy was performed using the Nd:YAG laser. Six laser sessions were necessary to destroy the whole adenoma. After 30 months of follow-up, there was neither endoscopic nor histologic recurrence. The laser therapy should be therefore considered in treating large sessile duodenal villous adenoma occurring in inope… Show more

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Cited by 8 publications
(3 citation statements)
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“…To date, there have no been reports of series of nonpolyposis pa− tients who have undergone endoscopic treatment of sporadic duodenal adenoma among the published papers which have de− scribed the use of this treatment modality for these tumors [2, 25 ± 29]. The only papers have been case reports of successful eradication of these polyps with additional endoscopic modal− ities, such as argon plasma coagulation and Nd−YAG laser [2,28,29]. The largest endoscopic study reports successful laser treatment in six patients after a median follow−up of almost 5 Original Article years [27]: the recurrence rate in this study was 28 %, with a fol− low−up period of 6 ± 78 months, which is lower than the recur− rence rate reported in surgically treated patients [23].…”
Section: Discussionmentioning
confidence: 99%
“…To date, there have no been reports of series of nonpolyposis pa− tients who have undergone endoscopic treatment of sporadic duodenal adenoma among the published papers which have de− scribed the use of this treatment modality for these tumors [2, 25 ± 29]. The only papers have been case reports of successful eradication of these polyps with additional endoscopic modal− ities, such as argon plasma coagulation and Nd−YAG laser [2,28,29]. The largest endoscopic study reports successful laser treatment in six patients after a median follow−up of almost 5 Original Article years [27]: the recurrence rate in this study was 28 %, with a fol− low−up period of 6 ± 78 months, which is lower than the recur− rence rate reported in surgically treated patients [23].…”
Section: Discussionmentioning
confidence: 99%
“…Historically, several complementary tissue destruction techniques had been used for nonampullary duodenal lesions. These included monopolar/bipolar coagulation, lasers such as the Nd-YAG [93][94][95], photodynamic therapy [96], and cryotherapy [97,98]. However, most of these have been abandoned because of lack of efficacy or unacceptable adverse events [95,96].…”
Section: Role Of Tumor-destruction Techniquesmentioning
confidence: 99%
“…This method presents a theoretical risk of hemorrhage and perforation, the latter being related to the maximal depth of coagulation, assessed as 4 mm. With regard to Nd: YAG la ser photodestruction of duodenal adenomas beside the pa pilla, the few case reports have not described perforation or massive bleeding [28,29]. In contrast, perforation or severe pancreatitis (4% of cases) was reported after endoscopic sphincterotomy, which is usually done before coagulation of ampullary adenomas.…”
Section: Endoscopic Coagulationmentioning
confidence: 99%