Endoscopic injection therapy in bleeding Mallory-Weiss syndrome: A randomized controlled trial

Endoscopic band ligation and endoscopic hemoclip placement for patients with Mallory-Weiss syndrome and active bleeding

“…Several endoscopic methods have been used to treat actively bleeding MWS, including injection of different agents, electrocoagulation, application of hemoclips, and band ligation [8,18] . Thermal coagulation or injection therapies have been used successfully to control active bleeding from MWS [10][11][12]21] . Laine [21] reported that effective for the control of active bleeding in patients with hemodynamically unstable MWS and/or combined major diseases.…”

“…However, repeated coagulation has the risk of producing transmural injury and perforation because the esophagus lacks serosa and is very thin at the tear site [22] . Injection therapy with various agents is an effective, simple, and inexpensive first-line approach [11,12] . Llach et al [11] .…”

“…Injection therapy with various agents is an effective, simple, and inexpensive first-line approach [11,12] . Llach et al [11] . Reported that endoscopic injection therapy using epinephrine and polidocanol improved outcomes (rate of recurrent bleeding, hospital stay, and transfusion requirement) compared with supportive measures alone in a prospective, randomized controlled trial.…”

“…In recent decades, endoscopic treatment has been the treatment of choice [8] . Various endoscopic techniques, mainly consisting of endoscopic coagulation or injection, have been used in the management of patients with MWS at high risk for recurrent bleeding [9][10][11][12] . However, injection hemostasis may be incomplete for patients with a large and/or long plexuses of vessels and coagulation has the risk of producing transmural injury and perforation due to relatively thin esophageal wall [13] .…”

Transcatheter arterial embolization for acute nonvariceal upper gastrointestinal bleeding: Indications, techniques and outcomes

“…Classically, Mallory-Weiss tears are mucosal lacerations at the gastroesophageal junction or in the cardia of the stomach [13]. These lesions can be associated with repeated retching or vomiting and are another important cause of nonvariceal UGIB.…”