Endoscopic hemostatic devices

Conway, Jason; Adler, Douglas G.; Diehl, David L.; Farraye, Francis A.; Kantsevoy, Sergey V.; Kaul, Vivek; Kethu, Sripathi R.; Kwon, Richard S.; Mamula, Petar; Rodriguez, Sarah A.; Tierney, William M.

doi:10.1016/j.gie.2008.12.251

Cited by 114 publications

(70 citation statements)

References 87 publications

(95 reference statements)

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“…An APC is a noncontact electrocoagulation device that uses high-frequency monopolar alternating current conducted to target tissues through ionized argon gas (argon plasma) (14). This causes tissue desiccation at the contact interface of target tissue (14).…”

Section: Endoscopic Apc Therapymentioning

confidence: 99%

Role of argon plasma coagulation in management of bleeding GI tumors: evaluating outcomes and survival

Thosani¹,

Rao

Ghouri

et al. 2015

Turk J Gastroenterol

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Background/Aims: Tumor related gastrointestinal (GI) bleeding is a challenging clinical problem in cancer patients. Argon plasma coagulation (APC) is preferred for the management of bleeding arterio-venous malformations. Our objective was to assess the role of APC in the management of bleeding GI tumors. Materials and Methods: This is a retrospective review of endoscopies performed at the UT MD Anderson Cancer Center over 3 consecutive years (2009)(2010)(2011). This study involved patients with primary or metastatic gastrointestinal cancer with suspected GI bleeding and interventions included were endoscopies with APC. Our main outcome measurements were immediate hemostasis rate, change in transfusion requirements, re-bleeding rate, and 30-day mortality. Results: Immediate hemostasis was achieved in all 10 (100%) patients, with either APC performed alone (8 patients) or with adjuvant epinephrine (2 patients). There were no procedure related complications. The pooled transfusion requirements for all 10 patients 48 hours prior to the procedure were 26 packed red blood cells units, 11 platelet units and 6 fresh frozen plasma units, while the overall requirements in the 48 hours after the procedure were 5 packed red blood cells units, 6 platelet units and no fresh frozen plasma units. Re-bleeding occurred in 3 (30%) patients during follow up. Thirty day mortality rate was 0%. Total of 7 (70%) of patients were able to continue cancer specific therapy of either chemotherapy, radiation or both. Conclusion: APC is feasible and safe in routine practice to manage bleeding GI tumors. It is very effective in achieving initial hemostasis (100%) and allows majority of the patients (70%) to undergo cancer specific therapy.

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Section: Endoscopic Apc Therapymentioning

confidence: 99%

Role of argon plasma coagulation in management of bleeding GI tumors: evaluating outcomes and survival

Thosani¹,

Rao

Ghouri

et al. 2015

Turk J Gastroenterol

View full text Add to dashboard Cite

show abstract

“…Colonic perforation especially right colon has been reported as high as 2.5% with thermal devices [15,95,96]. Distention of the GI tract with argon gas, submucosal emphysema, pneumomediastinum, pneumoperitoneum, and gas explosion has been reported as complications of ACP [95,97,98].…”

Section: Colonic Hemostasismentioning

confidence: 99%

“…There are multiple reports of premature deployment of the clip, and the failure to separate the clip from the catheter after deployment [95]. Colonic perforation, initial worsening bleeding, clip retention, immediate or delayed bleeding secondary to slippage of loop when using detachable loop ligating devices have been described [95,99].…”

Section: Colonic Hemostasismentioning

confidence: 99%

“…Colonic perforation, initial worsening bleeding, clip retention, immediate or delayed bleeding secondary to slippage of loop when using detachable loop ligating devices have been described [95,99].…”

Section: Colonic Hemostasismentioning

confidence: 99%

“…The complications of injection needles are usually related to injected substances such as cardiac arrhythmias and hypertension due to epinephrine, however, there are reports of needles separating from the catheter in the patient and requiring retrieval, and of needles failing to extend from their sheaths [95].…”

Section: Colonic Hemostasismentioning

confidence: 99%

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