Endoscopic full‐thickness resection of duodenal lesions—a retrospective analysis of 20 FTRD cases

Abstract

This study confirmed the feasibility of duodenal EFTR and indicates good efficacy and safety. Larger studies are needed to further investigate this novel technique.

Short- and long-term outcomes of endoscopic submucosal dissection for non-ampullary duodenal neuroendocrine tumors

“…EMR is associated with positive vertical margins, or a crush and burn effect on the resected specimen, which leads to difficulties in performing a precise pathological evaluation. Recently, endoscopic full-thickness resection (EFTR) with the full-thickness resection devise (FTRD; Ovesco Endoscopy, Tübingen, Germany) for duodenal tumors had been reported [31,32]. Bauder et al reported that complete resection rates were 80% in five subepithelial tumors treated by FTRD.…”

“…Bauder et al reported that complete resection rates were 80% in five subepithelial tumors treated by FTRD. Their results suggested that EFTR is effective for NAD-NET, but the evidence is insufficient because of the small sample size [32]. Therefore, at the moment, ESD is the preferred method for NAD-NET to ensure accurate pathological diagnosis and avoid additional surgical resection for residual tumor.…”

“…Therefore, duodenal ESD might be unacceptable in western countries. On the other hand, the efficacy of EFTR using an FTRD for duodenal superficial tumors has been reported [31,32]. Since the evidence of EFTR for duodenal NETs is still unclear, comparative studies of the efficacy and safety of ESD and EFTR are needed.…”

Endoscopic full-thickness resection in a recurrent perianastomotic esophagojejunal cancer followed by fully covered metal stent placement for lumen occlusion

“…To the best of our knowledge, this is the first published case in which EFTR has been used in a recurrent perianastomotic cancer in the upper gastrointestinal tract [1]. Moreover, stent placement was effective in resolving stenosis when EFTR was complicated by lumen occlusion.…”

Duodenal Neuroendocrine Tumour Resection with a New Duodenal Full-Thickness Resection Device

“…A full-thickness resection device (FTRD; Ovesco Endoscopy ® ) enables endoscopic transmural resection of suitable lesions with a fast minimally invasive technique [2]. A colonic FTRD was used for duodenal lesions as an "off-label" indication with good clinical outcomes and a complication rate comparable to duodenal endoscopic mucosal resection [3]. A duodenal FTRD (d-FTRD) with smaller diameter (19.5 vs. 21 mm), balloonassisted insertion and less clip interdental space was developed allowing easier upper oesophageal sphincter passage and minimising bleeding risk.We describe a 74-year-old male with a 10-mm postpyloric bulbar submucosal lesion (Fig.…”