Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease using multiple Plicator implants: 12-month multicenter study results

Abstract

Endoscopic full-thickness plication using multiple Plicator implants can be used safely and effectively to improve GERD symptoms and reduce medication use.

Evaluating outcomes of endoscopic full-thickness plication for gastroesophageal reflux disease (GERD) with impedance monitoring

“…These techniques include application of radiofrequency, injection or implantation of biopolymers, and endoluminal suturing [8][9][10][11][12][13][14][15][16][17] Endoscopic treatment strategies currently target PPI-dependent GERD patients with small (\3 cm) or no hiatal hernias who do not have severe esophagitis or Barrett's esophagus. To date, EndoCinch (CR Bard, Murray Hill, NJ, USA), Enteryx (Boston Scientific, Natick, MA, USA), Stretta system (Curon Medical Inc., Sunnyvale, CA, USA), and the Plicator (Ethicon Endosurgery, Sommerville, NJ, USA) have been studied in sham-controlled trials [16][17][18][19][20][21][22][23] Radiofrequency treatment (Stretta) has proved to be only modestly effective, whereas implantation techniques have been abandoned due to serious adverse events (Enteryx) and lack of long-term efficacy (Gatekeeper system [Medtronic, Inc., Minneapolis, MN, USA]) [8][9][10][11][12][13][14][15][16][17].…”

Endoscopic Treatment of Gastro Esophageal Reflux Disease: A Review of Techniques Currently in Use the Novelty of GERD-X

“…The room, where it is sucked the mucosa of the esophagogastric junction, enables suturing the tissue in a situation of stability, but, despite this, the long-term sealing of the method is not effective [1,2].…”

NOTES – gastroenterologische Perspektive

“…Hierfür wurden bisher Clips, Stapler oder endoskopische Nahtapparate evaluiert [36][37][38][39][40][41][42][43][44]. Die für die endoskopische Therapie der Refluxerkrankung entwickelten endoluminalen Nahtapparate können hier ebenfalls erfolgreich eingesetzt werden [45][46][47][48][49][50][51] …”