Endoscopic findings around the gastroesophageal junction: an experience from a tertiary hospital in Korea

Kim, Ji Hyun; Hwang, Jin Ki; Kim, Juhyung; Lee, Sehe Dong; Lee, Beom Jae; Kim, Jae Seon; Bak, Young Tae

doi:10.3904/kjim.2008.23.3.127

Cited by 10 publications

(10 citation statements)

References 24 publications

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“…However, other factor such as BMI, smoking, alcohol habit, or co-morbidities were comparable to the background population. 44 , 46 These factors were not significantly different among RE, NERD, and the reference group in our study.…”

Section: Discussioncontrasting

confidence: 55%

“…The previous study in Korea demonstrated health screening population have higher income and educational status compared with general Korean population. However, other factor such as BMI, smoking, alcohol habit, or co-morbidities were comparable to the background population 44,46. These factors were not significantly different among RE, NERD, and the reference group in our study.…”

Section: Discussioncontrasting

confidence: 46%

See 1 more Smart Citation

Overlap of Erosive and Non-erosive Reflux Diseases With Functional Gastrointestinal Disorders According to Rome III Criteria

Noh¹,

Jung²,

Kim³

et al. 2010

J Neurogastroenterol Motil

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Background/AimsGastroesophageal reflux disease (GERD) is increasing in Asian countries. Functional dyspepsia (FD) or irritable bowel syndrome (IBS) are also prevalent and commonly overlapped with GERD. This study was conducted to compare the proportion and risk factors for overlapping reflux esophagitis (RE) and non-erosive reflux disease (NERD) with functional gastrointestinal disorders (FGIDs).MethodsA total of 2,388 [male, 55.9%; mean age (± SD), 43.2 years (± 8.4)] Korean subjects who underwent the upper endoscopy for health screening were prospectively included. The subjects were asked about demographic, medical and social history by using a structured questionnaire, and FD and IBS were assessed according to the Rome III criteria.ResultsThe subjects with RE were 286 (12.0%, male 88.5%, 42.8 years) and 74 subjects had NERD (3.1%) while the prevalence of FD and IBS were 8.1% and 10.1%, respectively. The proportion of FD and IBS in NERD was higher than that of RE (74.3% vs. 10.5%, p = 0.000; 41.9% vs. 11.2%, p = 0.000, respectively). The epigastric pain syndrome (EPS) was more prevalent than postprandial distress syndrome in NERD. According to multiple regression analysis, high somatization score and the presence of FD increased the odd ratio for NERD. However, male gender and current smoker were significant risk factors for RE.ConclusionsCompared to RE, NERD is more frequently overlapped with FD, especially EPS, and also are associated with significantly increased frequency of IBS. Our data draws attention to the possibility of subgrouping FGIDs and GERD to be important in understanding the pathophysiology of these conditions.

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Section: Discussioncontrasting

confidence: 55%

Section: Discussioncontrasting

confidence: 46%

Overlap of Erosive and Non-erosive Reflux Diseases With Functional Gastrointestinal Disorders According to Rome III Criteria

Noh¹,

Jung²,

Kim³

et al. 2010

J Neurogastroenterol Motil

View full text Add to dashboard Cite

show abstract

“…The previous study in Korea demonstrated that the study of health screening population had higher income and educational status compared with general Korean population. However, other factor such as BMI, smoking, alcohol habit or co-morbidities were comparable to the background population 24,25. In the present study, these factors were not significantly different between cases and controls.…”

Section: Discussioncontrasting

confidence: 48%

Prevalence and Predictive Factors of Fecal Incontinence

Kang

Jung²,

Kwon³

et al. 2012

J Neurogastroenterol Motil

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Background/AimsMost previous epidemiologic studies about fecal incontinence were performed in specific populations in Korea. We aimed to estimate the prevalence and predictive factors of fecal incontinence in adult Korean population, both men and women aged 20 years and over.MethodsSubjects who had undergone medical check-up for health screening were enrolled. They completed the structured questionnaires, including demographics, gastrointestinal symptoms, medical and social histories, and also about their bowel habits. Logistic regression models were constructed to identify the predictive factors for having fecal incontinence.ResultsAmong the total of 1,149 subjects (mean age, 44.8 ± 10.2 years; 648 males), the overall prevalence of fecal incontinence was 6.4%, while the older group (> 50 years old) showed the higher prevalence than the younger group (≤ 50 years old) (10.4% vs 4.9%, P = 0.001) without gender difference. Most patients had mild fecal incontinence in 78.4%. By multivariate analysis, old ages (Odd ratio [OR], 3.1; 95% confidence interval [CI], 1.9-5.2; P < 0.001), watery stool (OR, 2.8; 95% CI, 1.5-4.9; P = 0.001) and functional diarrhea (OR, 2.7; 95% CI, 1.4-5.4; P = 0.004) were found to be independent predictors for fecal incontinence.ConclusionsThe prevalence of fecal incontinence in Korean adults was 6.4%, and it was significantly more prevalent in older people without any gender difference. Aging and diarrhea were independent predictive factors of fecal incontinence. Therefore, proper control of the bowel pattern would lead to the prevention of fecal incontinence.

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“…Furthermore, both the presence and size of the hiatal hernia were important, with majority of patients with severe esophagitis having hiatal hernia 50,54-57. This association between hiatal hernia and reflux esophagitis could also be observed in the studies from Eastern countries where the prevalence of GERD and reflux esophagitis is considered to be lower 58-62. As for Barrett's esophagus, it is strongly related to hiatal hernia,63 with hiatal hernia being present in a great majority (72% to 96%) of patients with Barrett's esophagus 51,64.…”

Section: Clinical Significance Of Hiatal Herniamentioning

confidence: 74%

Clinical Significance of Hiatal Hernia

Hyun¹,

Bak²

2011

Gut Liver

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130

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The relationship between hiatal hernias and gastroesophageal reflux disease (GERD) has been greatly debated over the past decades, with the importance of hiatal hernias first being overemphasized and then later being nearly neglected. It is now understood that both the anatomical (hiatal hernia) and the physiological (lower esophageal sphincter) features of the gastroesophageal junction play important, but independent, roles in the pathogenesis of GERD, constituting the widely accepted "two-sphincter hypothesis." The gastroesophageal junction is an anatomically complex area with an inherent antireflux barrier function. However, the gastroesophageal junction becomes incompetent and esophageal acid clearance is compromised in patients with hiatal hernia, which facilitates the development of GERD. Of the different types of hiatal hernias (types I, II, III, and IV), type I (sliding) hiatal hernias are closely associated with GERD. Because GERD may lead to reflux esophagitis, Barrett's esophagus and esophageal adenocarcinoma, a better understanding of this association is warranted. Hiatal hernias can be diagnosed radiographically, endoscopically or manometrically, with each modality having its own limitations, especially in the diagnosis of hiatal hernias less than 2 cm in length. In the future, high resolution manometry should be a promising method for accurately assessing the association between hiatal hernias and GERD. The treatment of a hiatal hernia is similar to the management of GERD and should be reserved for those with symptoms attributable to this condition. Surgery should be considered for those patients with refractory symptoms and for those who develop complications, such as recurrent bleeding, ulcerations or strictures.

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Endoscopic findings around the gastroesophageal junction: an experience from a tertiary hospital in Korea

Cited by 10 publications

References 24 publications

Overlap of Erosive and Non-erosive Reflux Diseases With Functional Gastrointestinal Disorders According to Rome III Criteria

Overlap of Erosive and Non-erosive Reflux Diseases With Functional Gastrointestinal Disorders According to Rome III Criteria

Prevalence and Predictive Factors of Fecal Incontinence

Clinical Significance of Hiatal Hernia

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