1993
DOI: 10.3109/00016489309126227
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Endoscopic Examination of the Upper Gastrointestinal Tract for the Presence of Second Primary Cancers in Head and Neck Cancer Patients

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Cited by 34 publications
(13 citation statements)
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“…In particular, all 7 cases of glottic cancer without complaints of hoarseness detected by internists performing gastroscopic or bronchoscopic examination were diagnosed at stage I. Tobacco and alcohol represent well‐known risk factors for the development of malignancies in the head and neck region and upper gastrointestinal tract . The Japan Tobacco Company reported smoking prevalence of 32.2% for men and 10.5% for women in Japan, and 81.8% of patients with glottic cancer in the present study were smokers.…”
Section: Discussionsupporting
confidence: 44%
“…In particular, all 7 cases of glottic cancer without complaints of hoarseness detected by internists performing gastroscopic or bronchoscopic examination were diagnosed at stage I. Tobacco and alcohol represent well‐known risk factors for the development of malignancies in the head and neck region and upper gastrointestinal tract . The Japan Tobacco Company reported smoking prevalence of 32.2% for men and 10.5% for women in Japan, and 81.8% of patients with glottic cancer in the present study were smokers.…”
Section: Discussionsupporting
confidence: 44%
“…Tobacco and alcohol represent well-known risk factors for the development of malignancies in the head and neck region and upper gastrointestinal tract. 8 The Japan Tobacco Company reported smoking prevalence of 32.2% for men and 10.5% for women in Japan, 9 and 81.8% of patients with glottic cancer in the present study were smokers. In our study, the percentage of smokers was higher among patients with glottic cancer without complaints of hoarseness than patients with glottic cancer with hoarseness.…”
Section: Discussionsupporting
confidence: 46%
“…3,8,9,[12][13][14][15][16]22 In addition, metachronous esophageal cancers have been identified at different intervals, and the risk does not seem to decrease with time. 29 Therefore, according to recent guidelines, at least a single endoscopy may be indicated to search for esophageal cancer in patients with HNSCC.…”
Section: Discussionmentioning
confidence: 99%
“…1 Alcohol and tobacco consumption are the main predisposing factors for the development of aerodigestive squamous cell cancer type, according to the theory of field cancerization. [2][3][4] In addition, recent epidemiological studies have indicated a possible carcinogenetic relationship between human papilloma virus infection and oropharingeal 5 and esophageal cancer, 6 at least in regions with a high incidence of esophageal carcinoma, such as certain Chinese geographic areas. 6,7 The most relevant factor associated with the occurrence of esophageal squamous cell cancer (ESCC) is the history of primary head and neck squamous cell cancer (HNSCC).…”
mentioning
confidence: 99%