Endoscopic Endonasal Resection of Sinonasal and Nasopharyngeal Pleomorphic Adenomas: A Case Series

Karligkiotis, Apostolos; Bozkurt, Gülpembe; Pietrobon, Giacomo; Battaglia, Paolo; Turri‐Zanoni, Mario; Chu, Francesco; Ansarin, Mohssen; Ottini, Giorgia; Luca, Marco De; Uccella, Silvia; Castelnuovo, Paolo

doi:10.5152/tao.2020.5382

Cited by 7 publications

(9 citation statements)

References 10 publications

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“…The mean age of patients with intranasal PA is 45.4 years ( 1 ); however, our patient was much older, 72 years of age. The most frequent symptom in these patients at presentation is unilateral nasal obstruction, as in our case, but they can also present with epistaxis, nasal mass, cheek or nasal swelling, external deformity, mucopurulent rhinorrhea, and epiphora ( 1 - 4 ).…”

Section: Discussionmentioning

confidence: 53%

“…Malignant transformation of PA has been reported, meaning carcinoma ex PA and malignant mixed tumor ( 1 , 2 , 4 ). The diagnosis of benign metastasizing PA of the salivary gland is extremely rare and still under debate ( 1 , 4 ).…”

Section: Discussionmentioning

confidence: 99%

“…They also found that sinonasal PA involves patients in the fifth decade of life on average, with some female predominance ( 1 ). Patients usually presented within 1 year of the onset of symptoms, with the most frequent symptom being unilateral nasal obstruction, followed by epistaxis ( 1 - 4 ). Karligkiotis et al .…”

Section: Introductionmentioning

confidence: 99%

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Intranasal Pleomorphic Adenoma Arising from the Lateral Nasal Wall

Jovančević

2023

ACC

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SUMMARY Pleomorphic adenoma is very rare in the sinonasal region, with the most common localization on the nasal septum, followed by lateral nasal wall. In the case presented, a 72-year-old woman was complaining of the right sided nasal obstruction without any other symptoms. The symptom started a year before and increased progressively. Anterior rhinoscopy revealed a mucosa-covered, smooth-surfaced, soft, polypoid, pale, grayish-pink in color mass in the right nasal cavity, approximately 2x2 cm in size. Nasal endoscopy showed the mass to have a broad base on the lateral nasal wall. Computerized tomography scan showed a homogeneous, solid soft tissue mass, 25x18x12 mm in size, which was attached to the lateral nasal wall, behind the nasal vestibule, just in front of the inferior turbinate. Endonasal endoscopic complete tumor excision was performed, during which some spillage of the tumor occurred. Histology diagnosis was pleomorphic adenoma of minor salivary glands. The patient was followed up on regular basis and had no tumor recurrence in the 6 th postoperative year. Intranasal pleomorphic adenoma arising from the lateral nasal wall in front of the inferior turbinate is extremely rare, so the presented case is probably the first ever published.

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Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 99%

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Intranasal Pleomorphic Adenoma Arising from the Lateral Nasal Wall

Jovančević

2023

ACC

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“…Only 20% of all pleomorphic adenoma originates from the minor salivary gland and among them, pleomorphic adenoma of the nasopharynx is uncommon [4]. Previously, there were 11 cases of nasopharyngeal pleomorphic adenoma reported in a study by Bowman et al and one patient reported by Karligkiotis et al, making a total of 12 cases seen in the literature [2,5]. Pleomorphic adenoma might be mistaken as a malignant neoplasm when it grows at unusual anatomical sites, such as the nasopharynx in this case.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of a Nasopharyngeal Pleomorphic Adenoma Mimicking a Nasopharyngeal Carcinoma

Razak¹,

Aziz²,

Hamizan³

et al. 2022

Cureus

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Pleomorphic adenoma is the most common benign pathology of the major salivary gland but rare in the minor salivary gland, especially in the nasopharynx, with only a few cases reported in the literature. A 76year-old lady presented with bilateral nasal blockage for one year secondary to a nasopharyngeal mass. Histopathological examination reported it to be nasopharyngeal carcinoma, but the mass persisted after a course of chemotherapy combined with radiotherapy. Upon repeat biopsy, the mass was found to be a pleomorphic adenoma. The patient underwent nasopharyngectomy without complications and no evidence of recurrence after 18 months of follow-up.

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“…Selten (in etwa 8 %) findet sich diese Entität auch in den kleinen Speicheldrüsen des oberen Respirationstrakts. Mögliche Lokalisationen sind die Mundhöhle, die Nasenhauptund Nasennebenhöhlen, der Pharynx, der Larynx, die Trachea und auch die Tränendrüsen [2,3,4].…”

Section: Diskussionunclassified