Endoscopic diagnosis and treatment of tumors

Aabakken, Lars

doi:10.1055/s-0029-1215090

Cited by 1 publication

(1 citation statement)

References 30 publications

(30 reference statements)

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“…It utilizes endoscopic tools to dissect lesions from the submucosa like superficial esophageal cancer or those with high-grade dysplasia. 17 18 So, ESD was chosen as the mode of therapy for this patient. Several studies have shown low mortality rates following ESD of isolated lesions.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Submucosal Dissection for Esophageal Squamous Cell High-grade Dysplasia in a Patient with Plummer Vinson Syndrome

Patil

Vadgaonkar

Dalal

et al. 2022

Journal of Digestive Endoscopy

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A 35-year female with Plummer Vinson syndrome (PVS) presented with a history of progressive dysphagia over six months, not responding to iron therapy and endoscopic dilatations. Her upper gastrointestinal endoscopy showed a post-cricoid web dilated using a Savary-Gilliard dilator. On NBI, a long segment circumferential lesion with abnormal microvascular architecture was noted in the mid esophagus. Biopsy showed high-grade dysplastic squamous epithelium. The patient underwent minimally invasive, circumferential endoscopic submucosal dissection (ESD) and received oral prednisolone to prevent stricture formation. Resected margins were free of dysplasia. At follow-up there was no evidence of recurrence or stricture formation. To our knowledge, this is the first case of PVS with squamous proliferation with high-grade dysplasia that was successfully treated with circumferential ESD. Screening endoscopy helps in the downstaging of early cancer, and timely intervention helps to treat this with a minimally invasive approach like ESD.

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Section: Discussionmentioning

confidence: 99%