Endoscopic Correction of Vesicoureteral Reflux in the Renal Transplant Candidate

Jackson, Craig; Kay, R. G.; Bretan, Peter N.; Novick, Andrew C.; Steinmuller, Donald

doi:10.1016/s0022-5347(17)38861-4

Cited by 15 publications

(2 citation statements)

References 10 publications

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“…The first reports of subureteric injections using Teflon had encouraging results in hemodialysis patients waiting for renal transplantation (65-80%) [5][6][7] . However, the fear of the migration of particles prevented widespread use of this substance [2,4] .…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Treatment of Vesicoureteral Reflux with Polydimethylsiloxane in Adults: Do Location and Appearance of the Ureteric Orifice Have a Role in the Success Rates?

Başok

Yıldırım²,

Atsu³

et al. 2008

Urol Int

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Introduction: Low success rate for high grade reflux and anatomical abnormality of ureteric orifices continues to be the most important dilemma of the endoscopic treatment of vesicoureteral reflux (VUR). The aim of this study was to evaluate the efficacy of endoscopic polydimethylsiloxane injection in adults with VUR concerning reflux severity and the status of the ureteric orifice. Materials and Methods: Fifty-three ureters (34 patients) were treated with endoscopic polydimethylsiloxane injection. The grade of VUR was I, II, III, IV and V in 2, 13, 25, 10 and 3 ureters, respectively.Any endoscopic characteristics of ‘golf hole’, broad appearance or lateral placement of ureteric orifices were classified as complex appearance ureters (CAU). Patients with persistent reflux were considered for second and third injections with the same material. Success was determined as no reflux. Results: The total success rate was 100, 92.30, 92, 80 and 66.66% for grade I, II, III, IV and V reflux after the third injection, respectively. The cure rates of ureters with normal appearance were 100, 88.88, 90, 100 and 100% for grade I, II, III, IV and V reflux. The cure rates of CAU were 100% for both grade II and III, 60% for grade IV and 50% for grade V reflux. The injected volumes per renal unit ranged between 0.2 and 3.2 ml (mean 1.05 ml). Conclusions: Although there are disadvantages in the usage of higher volumes of injectable material for successful results and difficulty in subureteral injection both in high grade reflux and complex anatomical situations in adults when compared to children, our results indicate that endoscopic treatment of VUR is an effective therapy for adults.

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Section: Discussionmentioning

confidence: 99%

Endoscopic Treatment of Vesicoureteral Reflux with Polydimethylsiloxane in Adults: Do Location and Appearance of the Ureteric Orifice Have a Role in the Success Rates?

Başok

Yıldırım²,

Atsu³

et al. 2008

Urol Int

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show abstract

“…This technique is sim ple, requires no open operation of the pretransplantation bladder and gives good results. Recent reports have shown that VUR can be corrected in children with an 87% success rate [8][9][10][11] and in renal transplantation candidates [12], However, there are still two problems with this endoscopic technique: the distant migration of the polytetrafluoroethylene particle (demonstrated in animal study) [ 13] and long-term results.…”

Section: Discussionmentioning

confidence: 99%

Vesicoureteral Reflux in the Renal Transplantation Candidate

Bouchot¹,

Guillonneau²,

Cantarovich³

et al. 1991

Eur Urol

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Endoscopic correction of primary vesicoureteric reflux by subureteric Teflon injection (STING): follow-up study in 123 patients

Puri

1991

Pediatr Surg Int

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Endoscopic Correction of Vesicoureteral Reflux in the Renal Transplant Candidate

Cited by 15 publications

References 10 publications

Endoscopic Treatment of Vesicoureteral Reflux with Polydimethylsiloxane in Adults: Do Location and Appearance of the Ureteric Orifice Have a Role in the Success Rates?

Endoscopic Treatment of Vesicoureteral Reflux with Polydimethylsiloxane in Adults: Do Location and Appearance of the Ureteric Orifice Have a Role in the Success Rates?

Vesicoureteral Reflux in the Renal Transplantation Candidate

Endoscopic correction of primary vesicoureteric reflux by subureteric Teflon injection (STING): follow-up study in 123 patients

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