Endoscopic capsule placement improves the completion rate of small-bowel capsule endoscopy and increases diagnostic yield

Gao, Youguang; Ge, Zhi Zheng; Chen, Hai-Ying; Li, Xiao Bo; Dai, Jun; Ye, Chen An; Xiao, Shu Dong

doi:10.1016/j.gie.2009.12.003

Cited by 38 publications

(30 citation statements)

References 15 publications

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“…This rate is higher than the incompletion rates in 2 studies that incorporated realtime image viewers to determine the need for endoscopic capsule deployment with incompletion rates of 13.6% and 14%. 8,21 A potential contributor to the higher incomplete examination rate in this study was our inclusion of all patients undergoing endoscopic capsule placement as opposed to the study by Gao et al, 8 which excluded patients with a history of abdominal surgery or a known neurologic disorder that could affect GI motility. Our series reflects a medically diverse patient population and provides insight into the use and completion rate of endoscopically deployed capsules in an unselected sample.…”

Section: Discussionmentioning

confidence: 98%

“…4 Incompletion rates of orally ingested capsules have been reported to be between 20% and 30%. [5][6][7][8] Prolonged gastric transit time, previous small-bowel surgery, poor bowel cleansing, 6 diabetes mellitus, 9 and inpatient status 10 have all been shown to be risk factors for incomplete CE examinations. Use of prokinetic agents as a way to reduce gastric transit time and increase the likelihood of a complete small-bowel examination has been met with conflicting results.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Endoscopic deployment of video capsule endoscopy: does it guarantee a complete examination of the small bowel?

Gibbs¹,

Bloomfeld²

2012

Gastrointestinal Endoscopy

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Endoscopic deployment of video capsule endoscopy: does it guarantee a complete examination of the small bowel?

Gibbs¹,

Bloomfeld²

2012

Gastrointestinal Endoscopy

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“…In our series, despite the reduction of IE, we did not find a significantly higher diagnostic yield in the RTV group (49% vs 39% in the control group). Recently, Gao et al [20] showed that delivering the capsule to the duodenum by upper endoscopy using a basket in patients with delayed gastric transit, identified with RTV, improved the rate of complete small-bowel examinations, resulting in higher diagnostic yield of SBCE. We could speculate whether it would be useful to routinely place the capsule in the duodenum with the AdvanCE ® from the beginning of the examination.…”

Section: Discussionmentioning

confidence: 99%

“…The new Given ® Data Recorder (DR3) with the real time viewer (RTV) enables real-time viewing during SBCE procedure ( Figure 1). The European Society of Gastrointestinal Endoscopy (ESGE) recommended that patients at increased risk for IE might benefit from the use of the RTV periprocedurally, with subsequent endoscopic placement of the capsule in the duodenum when indicated [20] . The aim of our study was to assess whether the prokinetic agent domperidone, in association with the RTV, could reduce the rate of IE and improve the diagnostic yield of SBCE.…”

Section: Introductionmentioning

confidence: 99%

Finding the solution for incomplete small bowel capsule endoscopy

Cotter¹,

Castro²,

Magalhães³

et al. 2013

WJGE

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AIM:To evaluate whether the use of real time viewer (RTV) and administration of domperidone to patients with delayed gastric passage of the capsule could reduce the rate of incomplete examinations (IE) and improve the diagnostic yield of small bowel capsule endoscopy (SBCE). METHODS:Prospective single center interventional study, from June 2012 to February 2013. Capsule location was systematically checked one hour after ingestion using RTV. If it remained in the stomach, the patient received 10 mg domperidone per os and the location of the capsule was rechecked after 30 min. If the capsule remained in the stomach a second dose of 10 mg of domperidone was administered orally. After another 30 min the position was rechecked and if the capsule remained in the stomach, it was passed into the duodenum by upper gastrointestinal (GI) endoscopy. The rate of IE and diagnostic yield of SBCE were compared with those of examinations performed before the use of RTV or domperidone in our Department (control group, January 2009 -May 2012). RESULTS:Both groups were similar regarding age, sex, indication, inpatient status and surgical history. The control group included 307 patients, with 48 (15.6%) IE. The RTV group included 82 patients, with 3 (3.7%) IE, P = 0.003. In the control group, average gastric time was significantly longer in patients with IE than in patients with complete examination of the small bowel (77 min vs 26 min, P = 0.003). In the RTV group, the capsule remained in the stomach one hour after ingestion in 14/82 patients (17.0%) vs 48/307 (15.6%) in the control group, P = 0.736. Domperidone did not significantly affect small bowel transit time (260 min vs 297 min, P = 0.229). The capsule detected positive findings in 39% of patients in the control group and 49% in the RTV group (P = 0.081). CONCLUSION:The use of RTV and selective administration of domperidone to patients with delayed gastric passage of the capsule significantly reduces incomplete examinations, with no effect on small bowel transit time or diagnostic yield. Cotter J et al . The importance of real time viewer peridone to patients with delayed gastric passage of the capsule assessed with the real time viewer (RTV) effectively reduces the rate of incomplete SBCE. The administration of domperidone does not influence small bowel transit time of the capsule. There is an overall trend towards higher diagnostic yield of SBCE when domperidone is selectively administered. The use of the RTV should be adopted systematically in patients undergoing small bowel capsule endoscopy.

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“…Prior studies have demonstrated upwards of 16-22% rates of incomplete small bowel examinations [7][8][9][10] . The PC was in line with these prior studies as it demonstrated a 15.7% rate of failure to achieve complete small bowel examination.…”

mentioning

confidence: 99%

A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope

Choi

Mergener²,

Semrad

et al. 2013

Gastrointestinal Endoscopy

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Endoscopic capsule placement improves the completion rate of small-bowel capsule endoscopy and increases diagnostic yield

Cited by 38 publications

References 15 publications

Endoscopic deployment of video capsule endoscopy: does it guarantee a complete examination of the small bowel?

Endoscopic deployment of video capsule endoscopy: does it guarantee a complete examination of the small bowel?

Finding the solution for incomplete small bowel capsule endoscopy

A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope

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