Endoscopic Approaches to Obesity

Štimac, Davor; Majanović, Sanja Klobučar

doi:10.1159/000336683

Cited by 25 publications

(12 citation statements)

References 74 publications

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“…Endoluminal sleeves and intragastric balloons have demonstrated short-term efficacy in inducing weight loss as well as concurrent resolution or improvement of obesity-related comorbidities [7]. A newly proposed technique, the laparoscopic fundoplication combined with mediogastric plication, has been reported to offer improvements in gastroesophageal reflux disease with excess weight loss approaching that of RYGB in patients with a BMI of 32–35 kg/m 2 after 1 year, although long-term data is lacking [8].…”

Section: Bariatric Surgerymentioning

confidence: 99%

Gastrointestinal changes after bariatric surgery

Quercia¹,

Dutia²,

Kotler³

et al. 2014

Diabetes & Metabolism

104

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Severe obesity is a preeminent health care problem that impacts overall health and survival. The most effective treatment for severe obesity is bariatric surgery, an intervention that not only maintains long-term weight loss but also is associated with improvement or remission of several comorbidies including type 2 diabetes mellitus. Some weight loss surgeries modify the gastrointestinal anatomy and physiology, including the secretions and actions of gut peptides. This review describes how bariatric surgery alters the patterns of gastrointestinal motility, nutrient digestion and absorption, gut peptide release, bile acids and the gut microflora, and how these changes alter energy homeostasis and glucose metabolism.

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Section: Bariatric Surgerymentioning

confidence: 99%

Gastrointestinal changes after bariatric surgery

Quercia¹,

Dutia²,

Kotler³

et al. 2014

Diabetes & Metabolism

104

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“…Currently, similar to bariatric surgery, there are 2 major approaches to endoscopic bariatric therapies: restrictive and malabsorptive (Figure ). The duodeno‐jejunal bypass sleeve (DJBS) is an example of malabsorptive therapy, whereas the restrictive procedures include adjustable intragastric balloons (IGBs), endoscopic sleeve gastroplasty (ESG), trans‐oral gastroplasty, and trans‐oral endoscopic restrictive implant system . Data are emerging to indicate that these procedures may also have significant benefit for patients with NAFLD.…”

Section: Endoscopic Proceduresmentioning

confidence: 99%

Evolution of NAFLD and Its Management

et al. 2019

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The global prevalence of nonalcoholic fatty liver disease (NAFLD) is estimated to be 25% and continues to rise worldwide in the setting of the obesity epidemic. This increase is especially concerning because NAFLD is often a progressive disease that can be associated with significant complications such as liver cirrhosis, hepatocellular carcinoma, and an increase in liver-related and overall mortality. Because of the devastating complications and comorbidities, NAFLD is a very costly disease for the healthcare system, with estimated annual direct medical costs exceeding $100 billion in the United States alone. Given this progressive course, it is imperative to make the diagnosis in patients with risk factors (metabolic syndrome, weight gain, and insulin resistance/diabetes). Once the diagnosis is made, the focus should shift to treatment and monitoring for the development of associated complications. Given that currently no pharmaceutical intervention is approved for the treatment of NAFLD, focus shifts instead to mitigation of risk factors through avoidance of foods that are rich in red meat, trans fats, refined carbohydrates, and high-fructose corn syrup; are low fiber; and have high energy density. The landmark of treatment, however, continues to be weight loss and improvement of insulin resistance, often through a multimodality approach. The current manuscript reviews the clinical phenotypes of NAFLD, its risk factors, and pathogenesis, as well as treatment options including lifestyle modifications and dietary interventions, medical therapies, endoscopic bariatric interventions, and bariatric surgery. (Nutr Clin Pract. 2020;35:72-84) Keywords fatty liver; insulin resistance; liver cirrhosis; non-alcoholic fatty liver disease; nutrition therapy; weight loss From the

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“…Recent surgical trends have sought to achieve a smaller scar and use a minimally invasive approach. Endoluminal bariatric procedures, which are performed using flexible endoscopy completely through the GI tract, offer the potential for an ambulatory weight loss procedure that may be more cost-effective and safer than current surgical bariatric procedures [ 11 ]. Endoscopic bariatric procedures have been attempted as a type of relatively noninvasive approach related to the restriction of food intake or malabsorption.…”

Section: Endoscopic Bariatric Procedures and Rolementioning

confidence: 99%

Role of Endoscopic Gastroplasty Techniques in the Management of Obesity

Jung

2017

Clin Endosc

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Health and wellness represent a major global concern. Trends such as a lack of exercise and excessive consumption of calories are major causes of the rapid increase in obesity worldwide. Obesity should be controlled because it can result in other illnesses, such as diabetes, high blood pressure, high cholesterol, coronary artery disease, stroke, breathing disorders, or cancer. However, many people have difficulty in managing obesity through exercise, dietary control, behavioral modifications, and drug therapy. Bariatric surgery is not commonly used due to a variety of complications, even though it has been demonstrated to produce reliable results with respect to adequate weight loss when performed using an open or a laparoscopic approach. Endoscopic bariatric procedures are emerging techniques that are less invasive and safer compared with current surgical approaches. However, the evaluation of endoluminal procedures is limited by the small number of studies and their short-term follow-up.

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Endoscopic Approaches to Obesity

Cited by 25 publications

References 74 publications

Gastrointestinal changes after bariatric surgery

Gastrointestinal changes after bariatric surgery

Evolution of NAFLD and Its Management

Role of Endoscopic Gastroplasty Techniques in the Management of Obesity

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