Endoscopic Approach to Intramural Ureter Pathology

Geavlete, P.; Georgescu, D.; Multescu, R.; Geavlete, Bogdan

doi:10.1016/b978-0-12-802439-3.00009-8

Cited by 2 publications

(3 citation statements)

References 163 publications

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“…The first formulation approved by the FDA for use in the treatment of vesicoureteral reflux was stabilized HA/dextranomer (NASHA/Dx) (Geavlete et al, 2016 ). HA-based devices for the prevention of surgical post adhesion is also well-documented (Chen C.-H et al, 2017 ; Li et al, 2017 ); Seprafilm® is an anti-adhesion film to reduce abdominopelvic post-surgical adhesions, comprised of crosslinked HA with carboxymethylcellulose (CMC) (Diamond et al, 2012 ).…”

Section: Introductionmentioning

confidence: 99%

An Effective Translation: The Development of Hyaluronan-Based Medical Products From the Physicochemical, and Preclinical Aspects

Huerta-Ángeles

Nešporová

Ambrožová

et al. 2018

Front. Bioeng. Biotechnol.

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This review shows the steps toward material selection focalized on the design and development of medical devices based on hyaluronan (HA). The selection is based on chemical and mechanical properties, biocompatibility, sterilization, safety, and scale-up costs. These facts play a vital role in the industrialization process. Approved medical devices containing-HA are illustrated to identify key parameters. The first part of this work involves the steps toward a complete characterization of chemical and mechanical aspects, reproducibility of the processes and scale up. In a second stage, we aimed to describe the preclinical in vitro and in vivo assays and selected examples of clinical trials. Furthermore, it is important to keep in mind the regulatory affairs during the research and development (R&D) using standardization (ISO standards) to achieve the main goal, which is the functionality and safety of the final device. To keep reproducible experimental data to prepare an efficient master file for the device, based on quality and recorded manufacturing data, and a rigorous R&D process may help toward clinical translation. A strong debate is still going on because the denominated basic research in HA field does not pay attention to the purity and quality of the raw materials used during the development. So that, to achieve the next generation of devices is needed to overcome the limitations of state of art in terms of efficacy, biodegradability, and non-toxicity.

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Section: Introductionmentioning

confidence: 99%

An Effective Translation: The Development of Hyaluronan-Based Medical Products From the Physicochemical, and Preclinical Aspects

Huerta-Ángeles

Nešporová

Ambrožová

et al. 2018

Front. Bioeng. Biotechnol.

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“…In humans, ectopic ureters are associated with a duplex renal system in 80% to 90% of cases, similarly with more females being affected than males (Decter 1997, Geavlete et al . 2016, Merguerian & Rowe 2018). In contrast, in the previously reported veterinary cases documenting duplex kidneys with ectopic ureters in dogs, four out of five were male (Esterline et al .…”

Section: Discussionmentioning

confidence: 99%

“…1989, Decter 1997, Geavlete et al . 2016, Merguerian & Rowe 2018). Based on the literature search, this phenomenon has only been described in dogs five other times in veterinary medicine (Esterline et al .…”

Section: Introductionmentioning

confidence: 99%

Urinary incontinence in a dog with a duplex renal system and extramural ectopic ureter

Greenfield

Berent

Weisse

2021

J of Small Animal Practice

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A 1‐year‐old female spayed French Bulldog was referred to the Interventional Radiology and Endoscopy Service for evaluation of urinary incontinence with partial response to medical management (phenylpropanolamine). Cystourethroscopy and retrograde ureteropyelogram were performed and revealed multiple congenital abnormalities including; a duplex renal system of the left kidney with one normal ureter with an intravesicular ureteral orifice and one extramural ectopic ureter with an associated branching and ureteral diverticulum. A dual vagina was also noted. Left neoureterocystostomy of the extramural ectopic ureter was performed and a temporary ureteral stent was concurrently placed and removed cystoscopically one month later, leaving the patient with two patent left ureters. Thirty‐four months later the patient is mildly incontinent with no other comorbidities.

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Endoscopic Approach to Intramural Ureter Pathology

Cited by 2 publications

References 163 publications

An Effective Translation: The Development of Hyaluronan-Based Medical Products From the Physicochemical, and Preclinical Aspects

An Effective Translation: The Development of Hyaluronan-Based Medical Products From the Physicochemical, and Preclinical Aspects

Urinary incontinence in a dog with a duplex renal system and extramural ectopic ureter

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