Endoscopic advances in the management of non-variceal upper gastrointestinal bleeding: A review

Naseer, Maliha; Lambert, Karissa; Hamed, Ahmed; Ali, Eslam

doi:10.4253/wjge.v12.i1.1

Cited by 28 publications

(32 citation statements)

References 90 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The etiology of non-variceal UGIB most commonly involves peptic ulceration/inflammation (most prevalent, approximately 50%), vascular lesions, congestive gastropathy, malignant lesions and other causes (Mallory-Weiss tears, Cameron ulcers, anastomotic ulcers, post-procedural hemorrhages). The etiology cannot be determined in about 10% of the patients (Table 1) (Naseer et al, 2020). Peptic ulcer disease is defined as a lesion that penetrates into the muscularis mucosa layer of the gastric and duodenal mucosa and is the most common cause of UGIB.…”

Section: Etiology Of Non-variceal Upper Gastrointestinal Bleedingmentioning

confidence: 99%

“…treatment. In the case of failure of conventional treatments, over the scope clips, hemostatic powder, endoscopic suture, endoscopic band ligation, coagrasper or hemostatic forceps, endoscopic ultrasound-guided angiography, cryotherapy, radiofrequency ablation and endoscopic laser coagulation are newer treatment modalities that can be used in UGIB (Naseer et al, 2020). Firstly, repeat endoscopy should be done in a recurring UGIB episode.…”

Section: Table 2 Forrest Classificationmentioning

confidence: 99%

See 1 more Smart Citation

Untitled

2021

J Exp Clin Med

View full text Add to dashboard Cite

Upper gastrointestinal bleeding (UGIB) is a common, life-threatening medical condition. Non-variceal causes account for more than 90% of bleeding episodes. Peptic ulcer disease is the most frequent cause of non-variceal UGIB. Patients present with hematemesis and/or melena but hematochezia might be present in patients with severe bleeding. Despite advances in diagnostic and therapeutic methods, mortality remains high in the elderly and patients with comorbidities. Endoscopy is the primary procedure that should be performed to identify the etiology of UGIB and for treatment purposes following adequate resuscitation of patients. Early endoscopy (within the first 24 hours) has considerably improved the clinical outcomes. A number of scoring systems are being used in patients with UGIB to identify the risk of complications, rebleeding risk, the need for interventional procedures and the risk of death. The most commonly used scoring tools are the Rockall score, Glasgow-Blatchford score and AIMS65 score. Primary treatment modalities include adequate resuscitation, intravenous fluid support, transfusion of red blood cell suspension, acid suppression therapy and administration of prokinetic agents. In general, angiography, computed tomography, technetium-99mlabeled red blood cell scintigraphy and capsule endoscopy may be used in patients whose bleeding cannot be detected endoscopically. Interventional radiological procedures should be initially performed for hemorrhages that cannot be stopped endoscopically and surgical options should be considered when interventional radiological procedures are out of reach or unsuccessful.

show abstract

Section: Etiology Of Non-variceal Upper Gastrointestinal Bleedingmentioning

confidence: 99%

Section: Table 2 Forrest Classificationmentioning

confidence: 99%

Untitled

2021

J Exp Clin Med

View full text Add to dashboard Cite

show abstract

“…In the management and treatment of Dieulafoy lesions, duodenal ulcers, Rouxen-Y gastric bypass, malignant gastric or esophageal lesions, pancreatic pseudoaneurysms, or gastrointestinal stromal tumors (GISTs), high success rates have been reported in several case series and studies. [22][23][24] EUS-guided angiotherapy was successfully applied in an elderly patient with a recurrent GI bleeding of a gastric GIST refractory to endoscopic over-thescope placement (Fig. 2 and Supplementary Video 5).…”

Section: Non-variceal Gastrointestinal Bleedingmentioning

confidence: 99%

“…Patients with non-variceal GI bleeding unsuccessfully treated with endoscopic means, or that are inapt for surgical, radiologic, or even endoscopic interventions, could benefit from EUS-guided hemostatic interventions too. In the management and treatment of Dieulafoy lesions, duodenal ulcers, Rouxen-Y gastric bypass, malignant gastric or esophageal lesions, pancreatic pseudoaneurysms, or gastrointestinal stromal tumors (GISTs), high success rates have been reported in several case series and studies [ 22 - 24 ]. EUS-guided angiotherapy was successfully applied in an elderly patient with a recurrent GI bleeding of a gastric GIST refractory to endoscopic over-thescope placement ( Fig.…”

Section: Non-variceal Gastrointestinal Bleedingmentioning

confidence: 99%

Endoscopic Ultrasound-Guided Vascular Procedures: A Review

2020

View full text Add to dashboard Cite

Since the 1980s, endoscopic ultrasound has advanced from being purely diagnostic to an interventional modality. The gastrointestinal tract offers an exceptional window for assessing the vascular structures in the mediastinum and in the abdomen. This has led to a rapidly growing interest in endoscopic ultrasound-controlled vascular interventions as a minimally invasive alternative to surgical and radiological procedures.

show abstract

“…Also available is the over-the-scope clip (OTSC) accessory (Ovesco Endoscopy AG, Germany; Padlock Clip Aponos Medical, USA), whose release is similar to an elastic band ligation procedure. The OTSC is mostly indicated for large and fibrotic ulcers, rescue therapy in non-variceal upper gastrointestinal bleeding, fistulas, perforations and dehiscence of anastomoses, or in other circumstances in which treatment with a TTS approach is difficult or fails [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Endoscopic clipping for gastrointestinal bleeding: emergency and prophylactic indications

Xavier

Campos

Robinson

et al. 2020

aog

View full text Add to dashboard Cite

Endoscopic clipping has become a common practice among endoscopists. Several models are available, most frequently being introduced via the working channel of the endoscope (through-the-scope); however, larger clips can also be mounted onto the distal tip of the endoscope (over-the-scope). The main indications for endoclip placement include providing effective mechanical hemostasis for bleeding lesions and allowing endoscopic closure of gastrointestinal perforations. Endoclips can also be used prophylactically after endoscopic resection; however, this practice is still controversial. This review discusses the main indications for endoscopic clipping in the esophagus, stomach, duodenum and colon to manage acute bleeding lesions, and the criteria to be used in the prevention of delayed post-polypectomy bleeding.

show abstract

Endoscopic advances in the management of non-variceal upper gastrointestinal bleeding: A review

Cited by 28 publications

References 90 publications

Untitled

Untitled

Endoscopic Ultrasound-Guided Vascular Procedures: A Review

Endoscopic clipping for gastrointestinal bleeding: emergency and prophylactic indications

Contact Info

Product

Resources

About