Endorectal power Doppler/grayscale ultrasound‑guided biopsies vs. multiparametric MRI/ultrasound fusion‑guided biopsies in males with high risk of prostate cancer: A prospective cohort study

He, Zhini; Yuan, Zhifan; Lin, Limei; Xie, Xinx In; Yuan, Jianjun; He, Wenxu; Chen, Junjun; Kuang, Yongpei

doi:10.3892/etm.2019.8151

Cited by 4 publications

(4 citation statements)

References 34 publications

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“…This is because there is a lack of studies that correlate Doppler ultrasound with radical prostatectomy results. From 2012 to 2023, four studies evaluated the performance of Doppler ultrasound in detecting prostate cancer, but the outcomes were based on biopsy results only [55][56][57][58]. The review was also supposed to discuss the results of multiparametric ultrasound in detecting prostate cancer, but only one study included in the review provided outcomes based on radical prostatectomy results.…”

Section: Discussionmentioning

confidence: 99%

The Performance of Different Parametric Ultrasounds in Prostate Cancer Diagnosis: Correlation with Radical Prostatectomy Specimens

Jawli,

Nabi,

Huang

2024

Cancers

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Background: Prostate cancer is a prevalent cancer among men. Multiparametric ultrasound [mpUS] is a diagnostic instrument that uses various types of ultrasounds to diagnose it. This systematic review aims to evaluate the performance of different parametric ultrasounds in diagnosing prostate cancer by associating with radical prostatectomy specimens. Methodology: A review was performed on various ultrasound parameters using five databases. Systematic review tools were utilized to eliminate duplicates and identify relevant results. Reviewers used the Quality Assessment of Diagnostic Accuracy Results [QUADAS-2] to evaluate the bias and applicability of the study outcomes. Result: Between 2012 and 2023, eleven studies were conducted to evaluate the performance of the different ultrasound parametric procedures in detecting prostate cancer using grayscale TRUS, SWE, CEUS, and mpUS. The high sensitivity of these procedures was found at 55%, 88.6%, 81%, and 74%, respectively. The specificity of these procedures was found to be 93.4%, 97%, 88%, and 59%, respectively. This high sensitivity and specificity may be associated with the large lesion size. The studies revealed that the sensitivity of these procedures in diagnosing clinically significant prostate cancer was 55%, 73%, 70%, and 74%, respectively, while the specificity was 61%, 78.2%, 62%, and 59%, respectively. Conclusions: The mpUS procedure provides high sensitivity and specificity in PCa detection, especially for clinically significant prostate cancer.

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Section: Discussionmentioning

confidence: 99%

The Performance of Different Parametric Ultrasounds in Prostate Cancer Diagnosis: Correlation with Radical Prostatectomy Specimens

Jawli,

Nabi,

Huang

2024

Cancers

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“…Previous studies showed that the probability of detecting clinically significant PCa increases with higher scores when prostate MRI is analyzed using the Likert scale or PI-RADS categorization [13,14]. Therefore, direct MRI-guided biopsy or cognitive or software-assisted MRI-US fusion biopsy can be more helpful than the conventional USguided biopsy in determining prostatectomy [15,16]. Fusion biopsy is a more convenient option, but since errors occurring in the process of registering two different types of images are inevitable, efforts are being made to reduce them.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Accuracies between Real-Time Nonrigid and Rigid Registration in the MRI–US Fusion Biopsy of the Prostate

et al. 2021

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Magnetic resonance imaging (MRI) is increasingly important in the detection and localization of prostate cancer. Regarding suspicious lesions on MRI, a targeted biopsy using MRI fused with ultrasound (US) is widely used. To achieve a successful targeted biopsy, a precise registration between MRI and US is essential. The purpose of our study was to show any decrease in errors using a real-time nonrigid registration technique for prostate biopsy. Nineteen patients with suspected prostate cancer were prospectively enrolled in this study. Registration accuracy was calculated by the measuring distance of corresponding points by rigid and nonrigid registration between MRI and US, and compared for rigid and nonrigid registration methods. Overall cancer detection rates were also evaluated by patient and by core. Prostate volume was measured automatically from MRI and manually from US, and compared to each other. Mean distances between the corresponding points in MRI and US were 5.32 ± 2.61 mm for rigid registration and 2.11 ± 1.37 mm for nonrigid registration (p < 0.05). Cancer was diagnosed in 11 of 19 patients (57.9%), and in 67 of 266 biopsy cores (25.2%). There was no significant difference in prostate-volume measurement between the automatic and manual methods (p = 0.89). In conclusion, nonrigid registration reduces targeting errors.

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“…Symptomatic men older than 40 years, 12 with prostate-specific antigen level 4.0 ng/mL or more, 13 and with abnormal digital rectal examination (increased stiffness of tissues; performed by urologists with a minimum of 3 years of experience of the institute) were referred from the urology clinic to the radiology clinic. Among them, men who reported suspicious lesions (lesions with an increased and rapid enhancement, for example, solid hypoechogenic mass) for prostate cancer under enhanced transrectal ultrasound (Doppler interrogation of the prostate; Fig.…”

Section: Methodsmentioning

confidence: 99%

Enhanced Transrectal Ultrasound, Real-Time Sonoelastography, and Contrast-Enhanced Transrectal Ultrasound in Heavily Prescreened Chinese Men With Naive and Repetitive Biopsy

Wang

Feng²,

Yang³

et al. 2022

Ultrasound Quarterly

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Multiparametric magnetic resonance imaging and targeted biopsy have been widely accepted as the most accurate technique to detect localize prostate cancer. It is a time-consuming and expensive option and may not be widely available in China, making ultrasound the first choice for the detection of prostate cancer. In this current retrospective study, the diagnostic values of enhanced transrectal ultrasound, contrast-enhanced transrectal ultrasound, and real-time sonoelastography were evaluated. Symptomatic 315 men older than 40 years with prostate-specific antigen level greater than 4.0 ng/mL, with abnormal digital rectal examinations, and with suspicious lesions for prostate cancer under enhanced transrectal ultrasound included in the study. Enhanced transrectal ultrasound was suspicious in all 315 men, with 189 of 315 men with prostate cancer according to the prostate biopsy report. Sonoelastography was suspicious in 294 of 315 men, with 166 of 315 men with prostate cancer according to the prostate biopsy report. Contrast-enhanced transrectal ultrasound was suspicious in 221 of 315 men, with 159 of 315 men with prostate cancer according to the prostate biopsy report. Real-time sonoelastography alone and contrast-enhanced transrectal ultrasound alone were missed in 27 (11%) and 39 (15%) lesions to report cancer through biopsies. Working area for enhanced transrectal ultrasound, real-time sonoelastography, and contrast-enhanced transrectal ultrasound for detection of prostate cancer were 0 to 1 diagnostic confidence, 0.11 to 0.895 diagnostic confidence, and 0.39 to 0.63 diagnostic confidence respectively. Real-time sonoelastography and contrast-enhanced transrectal ultrasound may improve the detection of prostate cancer in men with suspicious prostate lesions under enhanced transrectal ultrasound (Level of Evidence: III; Technical Efficacy Stage: 2).

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Endorectal power Doppler/grayscale ultrasound‑guided biopsies vs. multiparametric MRI/ultrasound fusion‑guided biopsies in males with high risk of prostate cancer: A prospective cohort study

Cited by 4 publications

References 34 publications

The Performance of Different Parametric Ultrasounds in Prostate Cancer Diagnosis: Correlation with Radical Prostatectomy Specimens

The Performance of Different Parametric Ultrasounds in Prostate Cancer Diagnosis: Correlation with Radical Prostatectomy Specimens

Comparison of Accuracies between Real-Time Nonrigid and Rigid Registration in the MRI–US Fusion Biopsy of the Prostate

Enhanced Transrectal Ultrasound, Real-Time Sonoelastography, and Contrast-Enhanced Transrectal Ultrasound in Heavily Prescreened Chinese Men With Naive and Repetitive Biopsy

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