Endoprosthesis Implantation in the Treatment of Recurrent Urethral Stricture: A Multicenter Study

Morgia, Giuseppe; Saita, Alberto; Morana, F.; Macaluso, Claudio; Serretta, Vincenzo; Lanza, P.; Capizzi, G.; Calarco, Alessandro; Zumbo, G.

doi:10.1089/end.1999.13.587

Cited by 14 publications

(4 citation statements)

References 10 publications

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“…There has previously been some interest into the use of urethral stents, both temporary and permanent for the treatment of anterior urethral strictures. Stents were associated with significant complications including perineal discomfort (86%), painful erection (44%) and recurrence (29%) in patients with short strictures using the UroLume stent [35] . Moreover, their use can make later reconstruction technically more difficult.…”

Section: Anterior Urethral Stricturesmentioning

confidence: 99%

Current trends in urethral stricture management

Hillary

Osman

Chapple

2014

Asian Journal of Urology

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The recent International Consultation on Urological Disease (ICUD) panel 2010 confirmed that a urethral stricture is defined as a narrowing of the urethra consequent upon ischaemic spongiofibrosis, as distinct from sphincter stenoses and a urethral disruption injury. Whenever possible, an anastomotic urethroplasty should be performed because of the higher success rate as compared to augmentation urethroplasty. There is some debate currently regarding the critical stricture length at which an anastomotic procedure can be used, but clearly the extent of the spongiofibrosis and individual anatomical factors (the length of the penis and urethra) are important, the limitation for this being extension of dissection beyond the peno-scrotal junction and the subsequent production of chordee. More recently, there has been interest in whether to excise and anastomose or to carry out a stricturotomy and reanastomosis using a Heineke-Miculicz technique. Augmentation urethroplasty has evolved towards the more extensive use of oral mucosa grafts as compared to penile skin flaps, as both flaps and grafts have similar efficacy and certainly the use of either dorsal or ventral positioning seems to provide comparable results. It is important that the reconstructive surgeon is well versed in the full range of available repair techniques, as no single method is suitable for all cases and will enable the management of any unexpected anatomical findings discovered intra-operatively.

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Section: Anterior Urethral Stricturesmentioning

confidence: 99%

Current trends in urethral stricture management

Hillary

Osman

Chapple

2014

Asian Journal of Urology

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“…The use of biodegradable materials has increased over the last decade in all fields of surgery, especially in urology [1]. The development of biodegradable stents for urological use started in the late 1980s, which is promising and ready to be tested in clinical trials [2]. The stents gradually achieved their properties of self-expansion and controlled gradual degradation [3].…”

Section: Introductionmentioning

confidence: 99%

Biodegradable urethral stent in the treatment of post-traumatic urethral strictures in a war wound rabbit urethral model

Fu¹,

Zhang²,

Gao³

et al. 2007

Biomed. Mater.

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To prevent terrorism during anti-terror war, we developed a reproducible animal model for the induction of a urethral stricture in a war wound rabbit, and to evaluate the feasibility and effect of using a biodegradable urethral stent in the prophylaxis and treatment of urethral strictures in a war wound (or traumatic) rabbit urethral model. The urethral stricture rabbit model was successfully performed by a self-control explosion destructor. New biodegradable urethral stents were placed in the urethras of 20 war wound (traumatic) rabbits, but no stent was used in the 8 rabbits which formed the control group. Follow-up investigation included assessment of procedure success, stent changes, urethrascopy and retrograde urethrography, and histological findings were obtained after sacrifice at 4, 6, 8 and 12 weeks after stent placement. The urethral stricture model owing to a war wound (trauma) was tested by tissue reactions and urethroscopy. The length of the urethral strictures was 5-10 mm; the coarctation of the urethral lumen was more than 50%. Biodegradable stent placement was technically successful in 20 rabbits. Urethral specimens obtained from the 4 week stent placement group showed diminished inflammatory cell infiltration and decreased thickness of the papillary projections of the epithelium. There was a strong tendency towards regression of the papillary projections and regeneration of urethral mucosa epithelium in the 8 week group. In particular, the injured urethra has recovered completely in the biodegradable stent groups compared with the control group at 12 weeks. The biodegradable urethral stent seems feasible for treating and preventing urethral strictures owing to a war wound (or traumatic) urethra. There are distinct advantages in terms of safe, effective and less-invasive treatment for the reconstruction of post-traumatic urethral strictures.

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“…6 More data revealed that patients experienced early complications of perineal discomfort (86%) and dribbling (14%) as well as painful erection (44%), mucous hyperplasia (44%), incontinence (14%) and recurrence (29%). 7 The urethral patency rate continued to decrease with time, as did patient satisfaction. De Vocht et al evaluated patient satisfaction 10 years after UroLume stent placement and found that only 2 of 15 were satisfied with the stent.…”

Section: Discussionmentioning

confidence: 91%

Removal of Endoprosthesis with Urethral Preservation and Simultaneous Urethral Reconstruction

Buckley

Zinman

2012

Journal of Urology

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Endoprosthesis Implantation in the Treatment of Recurrent Urethral Stricture: A Multicenter Study

Abstract: Permanent urethral endoprostheses can produce excellent results in patients with recurrent urethral strictures.

Cited by 14 publications

References 10 publications

Current trends in urethral stricture management

Current trends in urethral stricture management

Biodegradable urethral stent in the treatment of post-traumatic urethral strictures in a war wound rabbit urethral model

Removal of Endoprosthesis with Urethral Preservation and Simultaneous Urethral Reconstruction

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