Endoplasmic reticulum and Golgi apparatus: old friends, novel intimate relationships

Vitale, Alessandro

doi:10.1093/jxb/erx216

Cited by 3 publications

(1 citation statement)

References 21 publications

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“…These two compartments are closely associated with each other to facilitate movement of cargo between them. For example, the ER forms an extensive network throughout the plant cell, and the Golgi bodies are associated with ER in part through golgin-tethering complexes ( Osterrieder et al , 2017 ; see also the Insight article by Vitale and Pedrazzini, 2017 ). From the ER, these proteins are exported to the cis -side of the Golgi and are transported through the Golgi stacks where protein modifications such as glycosylation can occur.…”

Section: The Endoplasmic Reticulum As the Trafficking Start Pointmentioning

confidence: 99%

Protein and membrane trafficking routes in plants: conventional or unconventional?

Goring

Sansebastiano

2017

Journal of Experimental Botany

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Section: The Endoplasmic Reticulum As the Trafficking Start Pointmentioning

confidence: 99%

Protein and membrane trafficking routes in plants: conventional or unconventional?

Goring

Sansebastiano

2017

Journal of Experimental Botany

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Plant Endoplasmic Reticulum

Sparkes

2021

Encyclopedia of Life Sciences

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The plant endoplasmic reticulum (ER) is responsible for the synthesis and often storage of a large group of proteins and lipids that enter the secretory pathway. This multifunctional organelle, which also represents one of the calcium storage compartments in plant cells, has currently received considerable attention from the research community because of features unique to plants that make it particularly interesting for biotechnology. Here, the principles behind ER dynamics and interactions between the ER and organelles in plants, and the molecular factors that control the rapid remodelling and network configuration of the organelle are discussed. Correlations between ER morphology and function indicate the potential to enhance protein storage by merely increasing the capacity of the organelle through altering its shape. Key Concepts The endoplasmic reticulum in plants rapidly changes ‘shape’. The ER is composed of a polygonal network of tubules and cisternae (sheets) that readily interconvert. ER morphology is controlled by several molecular components; membrane shaping proteins, reticulons (RTNs), affect ER curvature, root hair defective 3 (RHD3) controls tubule fusion and is affected by lunapark. ER network movement is driven by actin and myosin in plants. The ER is physically connected to several organelles in plant cells.

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Research Progress in the Synthesis of Targeting Organelle Carbon Dots and Their Applications in Cancer Diagnosis and Treatment

Fan

Chen

et al. 2021

j biomed nanotechnol

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With increasing knowledge about diseases at the histological, cytological to sub-organelle level, targeting organelle therapy has gradually been envisioned as an approach to overcome the shortcomings of poor specificity and multiple toxic side effects on tissues and cell-level treatments using the currently available therapy. Organelle carbon dots (CDs) are a class of functionalized CDs that can target organelles. CDs can be prepared by a “synchronous in situ synthesis method” and “asynchronous modification method.” The superior optical properties and good biocompatibility of CDs can be preserved, and they can be used as targeting particles to carry drugs into cells while reducing leakage during transport. Given the excellent organelle fluorescence imaging properties, targeting organelle CDs can be used to monitor the physiological metabolism of organelles and progression of human diseases, which will provide advanced understanding and accurate diagnosis and targeted treatment of cancers. This study reviews the methods used for preparation of targeting organelle CDs, mechanisms of accurate diagnosis and targeted treatment of cancer, as well as their application in the area of cancer diagnosis and treatment research. Finally, the current difficulties and prospects for targeting organelle CDs are prospected.

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Endoplasmic reticulum and Golgi apparatus: old friends, novel intimate relationships

Abstract: This article comments on:Osterrieder A, Sparkes IA, Botchway SW, Ward A, Ketelaar T, de Ruijter N, Hawes C. 2017. Stacks off tracks: a role for the golgin AtCASP in plant endoplasmic reticulum–Golgi apparatus tethering. .

Cited by 3 publications

References 21 publications

Protein and membrane trafficking routes in plants: conventional or unconventional?

Protein and membrane trafficking routes in plants: conventional or unconventional?

Plant Endoplasmic Reticulum

Research Progress in the Synthesis of Targeting Organelle Carbon Dots and Their Applications in Cancer Diagnosis and Treatment

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