Endophthalmitis nach Bindehautperforation eines Glaukom-Gelstentimplantates

Moussaoui, Laila El; Djalali-Talab, Yassin; Walter, Peter; Plange, Niklas; Kuerten, David; Fuest, Matthias

doi:10.1007/s00347-020-01077-7

Ophthalmologe

2020

DOI: 10.1007/s00347-020-01077-7

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Endophthalmitis nach Bindehautperforation eines Glaukom-Gelstentimplantates

Laila El Moussaoui

Yassin Djalali-Talab

Peter Walter

et al.

Abstract: Eine 57-jährige Patientin mit primärem Offenwinkelglaukom hatte Ende 2018 eine kombinierte, unkomplizierte Kataraktoperation mit Implantation eines Glaukom-Gelstents (XEN ® 45 Gel Stent,

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Cited by 5 publications

(2 citation statements)

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“…After glaucoma filtration surgery, bleb-related endophthalmitis can occur. There are several cases of endophthalmitis after XEN45 Gel Stent implantation reported in the literature 2–4…”

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confidence: 99%

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A Case of Endocarditis Following Endophthalmitis After XEN45 Gel Stent Implantation

Wisdorf

Kowalski

Kiessling

et al. 2021

Journal of Glaucoma

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Introduction: We report a case of endophthalmitis and endocarditis that developed after stent perforation following a XEN45 Gel Stent implantation 10 months ago. Case Report: A 79-year-old man was referred to our hospital because of endophthalmitis of the right eye. The patient had undergone XEN45 Gel Stent implantation in the same eye 10 months ago. On examination, the conjunctiva was perforated by the stent, and it was no longer covered by the conjunctiva. A 27-G pars plana vitrectomy with intravitreal antibiotic injection was performed. Moreover, the patient received intravenous antibiotic treatment and local anti-inflammatory and anti-infectious therapy. Streptococcus gordonii was identified as a bacterial cause of the endophthalmitis. Therefore, transesophageal echocardiography was performed, which revealed aortic valve endocarditis. Discussion: Although not proven, it is possible that the exposed XEN45 Gel Stent served as an entry point for S. gordonii, which caused the exogenous endophthalmitis and subsequent endocarditis. S. gordonii belongs to the viridans group streptococci, which is the etiological agent for endocarditis which is a severe and potentially life-threatening infection. Ophthalmologists should therefore consider the risk of systemic infections as endocarditis after endophthalmitis, particularly caused by the viridans group streptococci, which are known etiological agents of endocarditis.

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“…After glaucoma filtration surgery, bleb-related endophthalmitis can occur. There are several cases of endophthalmitis after XEN45 Gel Stent implantation reported in the literature 2–4…”

mentioning

confidence: 99%

“…There are several cases of endophthalmitis after XEN45 Gel Stent implantation reported in the literature. [2][3][4] The XEN45 Gel Stent (Allergan, Irvine, CA) is an elastic, hydrophilic tube composed of porcine gelatin crosslinked with glutaraldehyde, which creates a drainage path from the anterior chamber to the subconjunctival space.…”

mentioning

confidence: 99%

A Case of Endocarditis Following Endophthalmitis After XEN45 Gel Stent Implantation

Wisdorf

Kowalski

Kiessling

et al. 2021

Journal of Glaucoma

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Why trabeculectomy is better than its reputation

Strzalkowska

Dietlein

Erb³

2022

Ophthalmologie

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Abiotrophia defectiva Endophthalmitis Post-Keratoplasty – A Case Report and Literature Review

Gushansky

2024

Ocular Immunology and Inflammation

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Endophthalmitis nach Bindehautperforation eines Glaukom-Gelstentimplantates

Abstract: Eine 57-jährige Patientin mit primärem Offenwinkelglaukom hatte Ende 2018 eine kombinierte, unkomplizierte Kataraktoperation mit Implantation eines Glaukom-Gelstents (XEN ® 45 Gel Stent,

Cited by 5 publications

References 10 publications

A Case of Endocarditis Following Endophthalmitis After XEN45 Gel Stent Implantation

A Case of Endocarditis Following Endophthalmitis After XEN45 Gel Stent Implantation

Why trabeculectomy is better than its reputation

Abiotrophia defectiva Endophthalmitis Post-Keratoplasty – A Case Report and Literature Review

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