“…Consistent with other reports, gram-positive organisms were the predominant pathogens, and Staphylococcus species remained to be the most common infectious organisms. 1,[9][10][11][12][13][14] The differences between this and previous reports included the present observation of a larger proportion of fungi than gram-negative organisms (18.4 vs.16.6) and the decrease in gram-negative organisms from 32% to 11% (P = 0.019) and increase in the percentage of gram-positive bacteria from 49% to 73% (P = 0.174) over a 10-year period, which disagree with the findings of a study by Gentile et al 15 The reasons for this difference remain unclear. Factors influencing variation between multiple reported studies include the period in time analyzed, prevalence of predisposing illnesses, geographic factors in organism incidence, urban versus rural settings, ethnicity, outpatient versus inpatient populations especially those in tertiary care centers, and climatic factors.…”