Endophthalmitis Following Pediatric Cataract Surgery: An International Pediatric Ophthalmology and Strabismus Council Global Perspective

Abstract

Endophthalmitis following pediatric cataract surgery is an uncommon, multifactorial complication with poor visual prognosis. Efforts directed at minimizing its risk, such as treating potential predisposing systemic conditions, improving sterilization techniques, optimizing operative conditions to reduce complications and surgery duration, and using subconjunctival and intracameral antibiotics, decrease its incidence. Early postoperative evaluation, subsequent follow-up visits, and keeping a high index of suspicion should facilitate the recognition of endophthalmitis following pediatric cataract surgery to avoid delaying treatment. [J Pediatr Ophthalmol Strabismus. 2018;55(1):23-29.].

Etiology, microbiological isolates, and antibiotic susceptibilities in culture-proven pediatric endophthalmitis: a 9-year review

“…Recent reports on pediatric endophthalmitis mostly focused on endophthalmitis due to a specific etiology such as pediatric cataract surgery [8], trauma [3,9], and endogenous infection [6] or focused on a specific type of endophthalmitis caused by a certain pathogen [10]. Only a few studies focused on pediatric endophthalmitis from all causes.…”

Endophthalmitis after pediatric cataract surgery in the United States: report using an insurance claims database

“…23,24 Given the increasing adoption of intracameral antibiotics by pediatric ophthalmologists as reported in a survey by Gharaibeh et al, one might expect a lower rate of postoperative endophthalmitis over time. 1 However, we show that cases endophthalmitis occurred throughout our 14-year study period. Further longitudinal evaluation using our data source needs to be conducted to comment on whether rates of endophthalmitis are changing over time in children after cataract surgery.…”

“…O ne of the most feared complications after cataract surgery is endophthalmitis, which has been reported to be more common and visually significant in children than in adults. 1 The incidence of endophthalmitis following pediatric cataract surgery is not well known due to the small number of cases and rarity of these particularly severe postoperative events. In adults, the incidence of endophthalmitis after cataract surgery has been reported to be between 0.02% and 0.2%, and the rate has declined over time.…”

The use of Aprokam® (cefuroxime sodium) in the management of post-operative infectious risk in pediatric cataract surgery

“…The study concluded that endophthalmitis, though multifactorial and fortunately infrequent, can be limited through proper sterilization techniques, favorable environmental conditions, and the use of intracameral and subconjunctival antibiotics. Early postoperative evaluation, follow-up visits, and a high index of suspicion are crucial for timely recognition and treatment [10].…”