Endophthalmitis Caused by Gram-Negative Bacteria

Relhan, Nidhi; Flynn, Harry W.

doi:10.1007/978-981-10-5260-6_17

Cited by 6 publications

(4 citation statements)

References 52 publications

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“…The main clinical signs of bacterial endophthalmitis are conjunctival hyperemia (SOSUAN; LEUENBERGER, 2020;WANG et al, 2020;BALASOIU et al, 2022), corneal edema (RELHAN; FLYNN, 2018;BHIKOO et al, 2022;KUMAR et al, 2022), blepharoedema (NIYADURUPOLA, 2018;NAKAI et al, 2019;KATOCH;DOGRA, 2020), conjunctival discharge (BAWANKAR et al, 2019;SINHA et al, 2021;AL-ABRI et al, 2022) and hypopyon (BRAZZANO et al, 2019;MAKUSHA et al, 2020;SASI et al, 2023), corroborating the signs presented by the patient described in this case.…”

Section: Discussionsupporting

confidence: 83%

Bacterial endoftalmitis caused by Serratia sp. in a bunny (Oryctolagus cuniculus)

Lira,

Almeida,

Perlmann

et al. 2023

Ii Seven International Congress of Health

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Literature Search MethodWe searched for articles in the literature written in English and Portuguese, as well as English translations of articles in other languages with the combination of keywords, Serratia, rabbit, endophthalmitis and gatifloxacin, in Medline, Lilacs, OPAS and SciELO through Google Scholar and by direct search, without temporal clipping, with refinement to the last five years, when possible.Individual case reports, case series and literature reviews on Serratia sp. induced endophthalmitis in all species were selected. Cross-references of those articles not highlighted in the cited research databases were also obtained and reviewed.

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Section: Discussionsupporting

confidence: 83%

Bacterial endoftalmitis caused by Serratia sp. in a bunny (Oryctolagus cuniculus)

Lira,

Almeida,

Perlmann

et al. 2023

Ii Seven International Congress of Health

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“…The main clinical signs of bacterial endophthalmitis are conjunctival hyperemia (SOSUAN;LEUENBERGER, 2020;WANG et al, 2020;BALASOIU et al, 2022), corneal edema (RELHAN;FLYNN, 2018;BHIKOO et al, 2022;KUMAR et al, 2022), blepharoedema (NIYADURUPOLA, 2018NAKAI et al, 2019;KATOCH;DOGRA, 2020), conjunctival secretion (BAWANKAR et al, 2019;Sinha et al, 2021;AL-ABRI et al, 2022) and hypopium (BRAZZANO et al, 2019;MAKUSHA et al, 2020;SASI et al, 2023), corroborating the signs presented by the patient described in this case.…”

Section: Discussionmentioning

confidence: 68%

Bacterial endophthalmitis caused by Serratia sp. nov. In rabbit (Oryctolagus cuniculus)

Lira,

Almeida,

Perlmann

et al. 2023

Iii Seven International Multidisciplinary Congress

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Bacterial endophthalmitis is a rare inflammation (TANAKA, 2019) that causes destruction and necrosis (TANAKA et al., 2011) of the structural components of the eyeball, through the penetration of infectious agents (JAIN et al., 2009; TIECCO et al., 2022) for the posterior segment of the eye, especially after intraocular surgeries (CARVALHO et al., 2021), traumas and systemic diseases (DURAND, 2017; TRAD et al., 2018; PUJARI et al., 2022), leading to vision loss (COELHO et al., 2015) and in more severe cases, enucleation (JACKSON, T. L. et al., 2014; JACKSON, TIMOTHY L. et al., 2014).

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“…Moxifloxacin has a dose-dependent action (aqueous concentration up to 300 times greater than the MIC). [ 26 27 28 ] Thus, intracameral moxifloxacin might have an advantage over the intracameral cefuroxime in the Indian context due to the higher incidence of gram-negative endophthalmitis. [ 29 ] But the current study showed that intracameral moxifloxacin does not necessarily prevent gram-negative infection.…”

Section: Discussionmentioning

confidence: 99%

Clinical features and microbiology of post-cataract surgery endophthalmitis with and without intracameral moxifloxacin prophylaxis: Endophthalmitis prophylaxis study report 3

Dave¹,

Singh

Reddy

et al. 2021

Indian Journal of Ophthalmology

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Purpose: This study aimed to analyze the clinical presentations, microbiology, and management outcomes of post–cataract surgery endophthalmitis, with and without intracameral moxifloxacin prophylaxis. Methods: This study was designed as a retrospective, consecutive, comparative case series. Records of consecutive cataract surgery from January 1, 2015, till June 30, 2020, were analyzed. The cases that developed endophthalmitis were analyzed. The endophthalmitis cases were divided by their prophylaxis treatment into two groups: with intracameral moxifloxacin (ICM) and without (N-ICM). Inclusion criteria were (1) age ≥ 18 years, (2) cataract surgery with intraocular lens implantation, (3) endophthalmitis within 6 weeks of cataract surgery, and (4) cataract surgery in the institute by any of the three methods—phacoemulsification, manual small incision cataract surgery, and extracapsular cataract extraction. Results: In the study period, 66,967 cataract surgeries were performed; 48.7% ( n = 32,649) did not receive ICM. There was no difference between the N-ICM and ICM groups in the incidence of clinical ( n = 21, 0.064% and n = 15, 0.043%; P = 0.23) and culture proven ( n = 19, 0.033% and n = 11, 0.023%; P = 0.99) endophthalmitis, respectively. Greater number of patients in the N-ICM group had lid edema (76.2% vs. 40%; P = 0.03), corneal edema (71.4% vs. 33.3%; P = 0.03) and lower presenting vision with available correction (logMAR [logarithm of the minimum angle of resolution] 1.26 ± 1.2 vs. logMAR 0.54 ± 0.85; P = 0.02). The final best-corrected visual acuity following treatment was worse in the N-ICM group (logMAR 1.26 ± 1.2 vs. 0.54 ± 0.85; P = 0.02). Conclusion: Endophthalmitis after intracameral moxifloxacin may have relatively milder signs and symptoms and may respond better to treatment.

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Endophthalmitis Caused by Gram-Negative Bacteria

Cited by 6 publications

References 52 publications

Bacterial endoftalmitis caused by Serratia sp. in a bunny (Oryctolagus cuniculus)

Bacterial endoftalmitis caused by Serratia sp. in a bunny (Oryctolagus cuniculus)

Bacterial endophthalmitis caused by Serratia sp. nov. In rabbit (Oryctolagus cuniculus)

Clinical features and microbiology of post-cataract surgery endophthalmitis with and without intracameral moxifloxacin prophylaxis: Endophthalmitis prophylaxis study report 3

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