Endomyocardial fibrosis with massive endocardial calcific deposits

Abstract

Summary:Massive endocardial calcific deposits in the left ventricular chamber is such an uncommon lesion that only three cases have been reported previously. This report describes an apparently asymptomatic patient with endomyocardial fibrosis and massive endocardial calcific deposits. The results of electrocardiography, echocardiography , angiography , and endomyocardial biopsy findings are presented, and the pathogenesis of massive endocardial calcification is speculated upon. The interesting point is that the clinical history and manifestation of this patient suggests that endomyocardial fibrosis may occur in a benign form and long-term survival may be expected.

Endomyocardial fibrosis in infancy

“…Evidence suggests the participation of eosinophils in the pathogenesis of endomyocardial fibrosis; endocardial fibrosis has been reported in patients with increased eosinophilia of several causes 9 . An increase in eosinophils was also observed in our patient (18% or 1422/mm 3 ), strengthening the suspicion of endomyocardial fibrosis.…”

“…It is more frequent from the fourth year of age on, with few reports in the first 2 years of life [5][6][7][8][9][10] .…”

Qual o seu diagnóstico?

“…It is a complex entity of yet undetermined etiology, endemic in several tropical countries, with varied forms of presentation, representing, in some regions, the primary cause of restrictive myocardiopathy. Possible etiologic factors are: serotoninrich diet, malnutrition, filariosis and viral diseases (1)(2)(3)(4)(5)(6) .…”

“…The presence of valvar insufficiency makes such manifestations even more noticeable. Such clinical manifestations differ according to the involvement of the cardiac chambers (predominance in right, left or both chambers) (1,3,9,(12)(13)(14)(15) .…”