Endometriosis: Molecular Pathophysiology and Recent Treatment Strategies—Comprehensive Literature Review
Marcin Sadłocha,
Jakub Toczek,
Katarzyna Major
et al.
Abstract:Endometriosis is an enigmatic disease, with no specific cause or trigger yet discovered. Major factors that may contribute to endometriosis in the pelvic region include environmental, epigenetic, and inflammatory factors. Most experts believe that the primary mechanism behind the formation of endometrial lesions is associated with Sampson’s theory of “retrograde menstruation”. This theory suggests that endometrial cells flow backward into the peritoneal cavity, leading to the development of endometrial lesions… Show more
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