Endometriosis and Ivf: Effect of Prior Therapy

Wardle, Peter G.; Foster, P.A.; Mitchell, J.D.; McLaughlin, Eileen A.; Sykes, J.; Corrigan, Elizabeth; Hull, M. G. R.; Ray, B.D.; McDermott, Alan

doi:10.1016/s0140-6736(86)90815-9

Cited by 38 publications

(20 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mechanism of endometriosis-associated infertility is not well understood. It is considered that the poor outcome associated with endometriosis is because of altered folliculogenesis (13), embryo toxicity against early embryotic development (14), and impaired fertilization (15). A good outcome of IVF-ET is dependent on the oocyte quality, embryo quality, and endometrial surroundings for embryo implantation.…”

Section: Discussionmentioning

confidence: 99%

Survivin gene expression in granulosa cells from infertile patients undergoing in vitro fertilization–embryo transfer

Fujino

Yamashita

Hayashi

et al. 2008

Fertility and Sterility

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Survivin gene expression in granulosa cells from infertile patients undergoing in vitro fertilization–embryo transfer

Fujino

Yamashita

Hayashi

et al. 2008

Fertility and Sterility

View full text Add to dashboard Cite

“…This was not found by Chillik et al (1985) or by Yovich et al (1985) who found that reproductive potential was severely impaired in the group with severe endometriosis. Nevertheless Wardle et al (1986) have demonstrated that different results were obtained when the endometriosis was treated as compared with a nontreated group. …”

Section: Discussionmentioning

confidence: 98%

Laparoscopic control of Danazol therapy on pelvic endometriosis

1988

View full text Add to dashboard Cite

In order to evaluate the efficiency of Danazol treatment on pelvic endometriosis, a laparoscopic control with photographs was performed before treatment in 33 cases. Of these 20 were severe (group A), seven mild (group B) and six light (group C), according to the American Fertility Society classification, and 15 patients were infertile, 10 had pelvic pain and eight had dysmenorrhoea. Among the 28 patients who accepted a laparoscopic control after 6 months of treatment, the result was quite good in 50% of the cases in groups B and C, an improvement was seen in 30% of the patients in groups A and B, but a failure in 50% of the cases, especially in group A. Of the 14 cases with an ovarian cyst greater than 3 cm in diameter an operation was necessary either by laparoscopy (four cases) or by laparotomy (five cases). Seven pregnancies were established out of 15 cases of infertility, but a relapse was noticed in 30% of the cases. In conclusion, it appears that Danazol therapy is effective in mild or light endometriosis, but is not sufficient in cases of ovarian endometriosis with cysts greater than 3 cm in diameter.

show abstract

“…However, the literature is not conclusive on this issue [28][29][30]. It is worth of note that ICSI is being utilized more frequently in these patients in view of reports of decreased fertilization rate after traditional IVF/ET [29,31,32]. Some reports suggested that ICSI can overcome apparent defects in oocytes derived from endometriosis patients [33].…”

Section: Discussionmentioning

confidence: 99%

Unilateral versus bilateral adnexal disease in stage III and stage IV endometriosis does not affect pregnancy outcome after operative laparoscopy

et al. 2008

View full text Add to dashboard Cite

To study the effect of unilateral versus bilateral adnexal involvement on the pregnancy rate after operative laparoscopy. Historic cohort study. A total of 143 patients with advanced stages of endometriosis (stage III and IV) who underwent operative laparoscopy for infertility treatment were categorized into those with unilateral versus bilateral adnexal disease. Forty-three patients had primarily unilateral (group 1) and 100 had bilateral disease (group 2). Follow-up was up to 2 years. There was no significant difference between group 1 and group 2 with respect to pregnancy rates (28% vs 31%), delivery rates (21% vs 23%), miscarriage rates (25% vs 13%), and ectopic rates (0% vs 13%). Cumulative conception rates after up to 24 cycles of natural intercourse and up to three IUI cycles were 59% and 49% for group 1 and group 2, respectively. Operative laparoscopy for advanced stages of endometriosis appears to be an effective treatment modality for establishing a pregnancy in infertile patients. Pregnancy and delivery rates are not different in patients with unilateral or bilateral adnexal involvement.

show abstract

Endometriosis and Ivf: Effect of Prior Therapy

Cited by 38 publications

References 6 publications

Survivin gene expression in granulosa cells from infertile patients undergoing in vitro fertilization–embryo transfer

Survivin gene expression in granulosa cells from infertile patients undergoing in vitro fertilization–embryo transfer

Laparoscopic control of Danazol therapy on pelvic endometriosis

Unilateral versus bilateral adnexal disease in stage III and stage IV endometriosis does not affect pregnancy outcome after operative laparoscopy

Contact Info

Product

Resources

About