Endometrial TGFβ signaling fosters early pregnancy development by remodeling the fetomaternal interface
Sydney E. Parks,
Ting Geng,
Diana Monsivais
Abstract:The endometrium is a unique and highly regenerative tissue with crucial roles during the reproductive lifespan of a woman. As the first site of contact between mother and embryo, the endometrium, and its critical processes of decidualization and immune cell recruitment, play a leading role in the establishment of pregnancy, embryonic development, and reproductive capacity. These integral processes are achieved by the concerted actions of steroid hormones and a myriad of growth factor signaling pathways. This r… Show more
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