Endometrial carcinoma

Abstract

Endometrial cancer is a common tumor of the female genital tract. The majority of women diagnosed with endometrial cancer present with early-stage disease. Although the optimal treatment for these patients requires hysterectomy, the use of lymphadenectomy is controversial. Growing scientific data support the use of lymphadenectomy in all patients diagnosed with endometrial cancer. When performed by an experienced surgeon, pelvic and para-aortic lymphadenectomy is a safe and potentially therapeutic procedure that provides prognostic information to the patient and physician. This information allows appropriate, cost-effective treatment strategies to be created for all women with endometrial cancer.

Controversies in the management of endometrial cancer: a survey of the Korean Gynecologic Oncology Group

“…For the extent of surgery for presumed low-risk endometrial cancer, there was a significant difference in opinion among the KGOG respondents, and we found a clear discrepancy between the clinical guidelines and the actual practice adopted by clinicians. As two large randomized controlled trials have demonstrated that comprehensive surgical staging does not improve progression-free or overall survival [ 5 6 ], the current National Comprehensive Cancer Network (NCCN) guidelines recommend a more selective and tailored lymphadenectomy approach in early-stage endometrial cancer [ 9 10 ]. In this survey, we observed that approximately 60% of respondents recommended lymphadenectomy at least at the pelvic level.…”