Endolichenic Fungi from Common Lichens as New Sources for Valuable Bio-active Compounds

Santiago, Krystle Angelique A.; Ting, Adeline Su Yien

doi:10.1007/978-981-13-7154-7_4

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Strategies For the Biodiscovery Of Novel Bioactive Metabolit...1

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2021

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“…Among these strategies is the OSMAC or "one strain, many compounds" approach. It is a simple yet effective strategy that aims to increase the number of secondary metabolites produced by a target microorganism by altering the fermentation conditions, such as media composition, temperature, pH, aeration, and addition of enzymes [77]. Wang and colleagues [78] applied such strategy to the ELF Ulocladium sp.…”

Section: Strategies For the Biodiscovery Of Novel Bioactive Metabolit...mentioning

confidence: 99%

In pursuit of promising microbes for drug discovery: tapping endolichenic fungi (ELF) from lichens

Cruz¹,

Santiago²

2021

actamanil

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The emergence of novel and re-emergence of latent infectious diseases coupled with rising cases of antimicrobial resistance necessitates the continuous search for new antibiotics. The Kingdom Fungi has been at the centerpiece of any drug discovery program ever since the beginning of the antibiotic era.The key strategy is to find novel taxa and/or ecologically defined fungal groups for the screening of bioactive secondary metabolites. In this paper, we presented the endolichenic fungi as promising fungi for bioprospecting. We searched for published papers on these fungi and presented reports of their biological activities. Through this paper, we hope to increase interest on these microorganisms among natural product researchers.

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Section: Strategies For the Biodiscovery Of Novel Bioactive Metabolit...mentioning

confidence: 99%

In pursuit of promising microbes for drug discovery: tapping endolichenic fungi (ELF) from lichens

Cruz¹,

Santiago²

2021

actamanil

View full text Add to dashboard Cite

show abstract

Endolichenic Fungi from Common Lichens as New Sources for Valuable Bio-active Compounds

Cited by 1 publication

References 70 publications

In pursuit of promising microbes for drug discovery: tapping endolichenic fungi (ELF) from lichens

In pursuit of promising microbes for drug discovery: tapping endolichenic fungi (ELF) from lichens

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