Endogenous Tissue Engineering for Chondral and Osteochondral Regeneration: Strategies and Mechanisms
Yanan Zhang,
Jialin Chen,
Yuzhi Sun
et al.
Abstract:Increasing attention has been paid to the development of effective strategies for articular cartilage (AC) and osteochondral (OC) regeneration due to their limited selfreparative capacities and the shortage of timely and appropriate clinical treatments. Traditional cell-dependent tissue engineering faces various challenges such as restricted cell sources, phenotypic alterations, and immune rejection. In contrast, endogenous tissue engineering represents a promising alternative, leveraging acellular biomaterial… Show more
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