Endogenous Retrovirus Loci and Induced Changes in Gene Expression in Japanese Indigenous Chickens
Shinya Ishihara,
Jun-ichi Shiraishi,
Saki Shimamoto
et al.
Abstract:SummaryWhen retroviruses infect germ cells and are transmitted to offspring, they become endogenous retroviruses (ERVs), whose insertions influence the expression of nearby genes. This study aimed to identify the genomic loci of ERVs in commercial broiler (Ross308), Tosa-Jidori, and Yakido chickens as well as to elucidate their impact on neighboring gene expression. Whole-genome data were obtained using next-generation sequencing, and candidate ERV loci were identified using the RetroSeq software. The Integrat… Show more
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