Endogenous Klebsiella Endophthalmitis Associated with Pyogenic Liver Abscess

Yang, Chi; Tsai, Hsien Yang; Sung, Chun Sung; Lin, Keng Hung; Lee, Fenq Lih; Hsu, Wen-Ming

doi:10.1016/j.ophtha.2006.12.035

Cited by 125 publications

(128 citation statements)

References 28 publications

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“…In the current case, as mentioned above, DWI, ADC and FLAIR sequences were useful for diagnosing endophthalmitis, and DWI and ADC were also valuable to reach the diagnosis of brain abscess. To our knowledge, imaging findings of bacterial endophthalmitis with brain abscess have been reported several times in English (7)(8)(9). However, this is the first report of imaging findings of simultaneously developed bacterial endophthalmitis with brain abscess on DWI and ADC.…”

Section: Index Words : Endophthalmitis•brain Abscess•magnetic Resonanmentioning

confidence: 77%

MRI Imaging of Simultaneously Developed Endogenous Endophthalmitis and Brain Abscesses

Kim

Chang

Kim

et al. 2013

J Korean Soc Magn Reson Med

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Section: Index Words : Endophthalmitis•brain Abscess•magnetic Resonanmentioning

confidence: 77%

MRI Imaging of Simultaneously Developed Endogenous Endophthalmitis and Brain Abscesses

Kim

Chang

Kim

et al. 2013

J Korean Soc Magn Reson Med

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“…We did not detect changes in the peripheral blood cell numbers. However, the infection with 3x10 Yang et al, 2007;Hui et al, 2007;Dhingra, 2008). Among the molecular structures often described related to the pathogenicity of K. pneumoniae, the clinical highlights are: K. pneumoniae capsular polysaccharide serotypes K1 and K2 (Pan et al, 2008;Clements et al, 2008); Presence of 8 out of the 12 LPS serotypes described (Whitfield et al, 1992); Production of the siderophores aerobactin, enterobactin, salmochelin and yersiniabactin .…”

Section: Issn: 2319-7706 Volume 6 Number 12 (2017) Pp 2525-2537mentioning

confidence: 99%

Intradermal Immunization of BALB/C Mice with Heat Killed Klebsiella pneumoniae ATCC BAA1706 Leads to the Production of both IgG1 and IgG2a

Pereira¹,

Galantine²,

Muniz³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

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“…The underlying source of the infection is a hepatic abscess in more than 50% of patients, and diabetes mellitus appears to be a predisposing factor in more than 75% of patients. 3,4 Metastatic complications, particularly endophthalmitis, are common. 4 The emergence of K. pneumoniae endophthalmitis probably reflects a changing epidemiology of liver abscess in Southeast Asia.…”

Section: 3mentioning

confidence: 99%

“…The magA gene is strongly associated with the K1 capsular serotype. 3,5 In the United States, recent reports of a similar clinical syndrome of K. pneumoniae liver abscess complicated by endophthalmitis may be related to immigration of individuals from endemic countries with potential redistribution of magA positive K1 K. pneumoniae strains into North America. Klebsiella pneumoniae is now the most common cause of liver abscess in the United States, overtaking Escherichia coli.…”

Section: 3mentioning

confidence: 99%

“…Klebsiella pneumoniae is now the most common cause of liver abscess in the United States, overtaking Escherichia coli. 3,5 The association between K. pneumoniae hepatic abscess and diabetes may result from impaired phagocytosis and chemotaxis in patients with diabetes. A recent case-control study showed that the presence of a K. pneumoniae liver abscess, but not ethnic background or diabetes mellitus, is a risk factor for K. pneumoniae endophthalmitis.…”

Section: 3mentioning

confidence: 99%

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Endogenous Klebsiella endophthalmitis in a Vietnamese immigrant

Sharma¹,

Chow²,

Muller³

2009

Canadian Medical Association Journal

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A previously healthy 54-year-old carpenter presented with a 13-day history of redness, tearing and pain in his left eye, which was associated with a progressive reduction in visual acuity. He had no fever or other systemic symptoms. He had no history of eye trauma or surgery, and he regularly used eye protection at work. He reported no intravenous drug use. He had immigrated to Canada from Vietnam 14 years before presentation, and his last trip to Vietnam was 7 months before the onset of illness. He initially sought medical attention 1 day after the onset of symptoms, and he was given gentamicin eyedrops for presumed conjunctivitis. After his symptoms did not improve, he was referred to an ophthalmologist.On examination, his visual acuity was bare light perception in the left eye and 20/40 in the right eye. He had eyelid and conjunctival swelling in the left eye (Figure 1). No hypopyon was seen. Examination with a slit lamp showed corneal edema with 4+ leukocytes (greater than 50 cells visualized) and flare (reflection of light from protein in the aqueous humour) in the anterior chamber. Fibrin was also present in the anterior chamber. The fundus could not be seen. The results of an examination of the patient's right eye were unremarkable. The patient did not have a fever, and the rest of a physical examination, including an abdominal exam, was unremarkable. A presumptive diagnosis of left endogenous endophthalmitis was made. A tap of the vitreous and anterior chamber of the patient's left eye was performed, and 1.0 mg vancomycin and 2.25 mg ceftazidime were administered into the vitreous.Within 48 hours, Klebsiella pneumoniae grew in a culture from the vitreous. The patient was admitted to hospital, and infectious disease specialists were consulted. By this time, the patient had increasing eye pain and lid swelling. The results of a physical examination were otherwise unchanged. Laboratory data obtained on admission were within normal ranges, except for a leukocyte count of 15.5 (normal 4-11) × 10 9 /L with 92% neutrophils. Liver function tests were not performed. Blood and urine cultures were negative. A computed tomography (CT) scan of the orbit of his left eye (Figure 2) showed periorbital swelling with marked proptosis.Given the potential association of K. pneumoniae liver abscess and K. pneumoniae endophthalmitis, a CT scan of the patient's abdomen was performed, which showed a complex 4.7 × 2.7 cm hypodense mass with multiple septations in the right lobe of his liver (Figure 3). Ultrasound-guided percutaneous drainage of the mass was performed, and culture of the fluid yielded K. pneumoniae.The K. pneumoniae isolates were sensitive to all antimicrobials tested, and the patient was given intravenous ceftri- Key points• Acute endophthalmitis should be considered in patients with blurred vision, ocular pain and redness, particularly in those with risk factors for endogenous or exogenous endophthalmitis.• It requires urgent referral to an ophthalmologist.• In a patient with endophthalmitis due to Klebsiella ...

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Endogenous Klebsiella Endophthalmitis Associated with Pyogenic Liver Abscess

Cited by 125 publications

References 28 publications

MRI Imaging of Simultaneously Developed Endogenous Endophthalmitis and Brain Abscesses

MRI Imaging of Simultaneously Developed Endogenous Endophthalmitis and Brain Abscesses

Intradermal Immunization of BALB/C Mice with Heat Killed Klebsiella pneumoniae ATCC BAA1706 Leads to the Production of both IgG1 and IgG2a

Endogenous Klebsiella endophthalmitis in a Vietnamese immigrant

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