Endogenous Fluorescence Carbon Dots Derived from Food Items

Wang, Haitao; Su, Wentao; Tan, Mingqian

doi:10.1016/j.xinn.2020.04.009

Cited by 48 publications

(45 citation statements)

References 121 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The impact of nanoparticles produced during food thermal processing on human health has received considered attention in the research field of food safety [1]. When nanoparticles enter the human body with food, they can inevitably interact with epithelial cells in the gastrointestinal tract, pass through the mucosa, enter the capillaries and distribute in organs and tissues [2].…”

Section: Introductionmentioning

confidence: 99%

Interaction of Carbon Dots from Grilled Spanish Mackerel with Human Serum Albumin, γ-Globulin and Fibrinogen

Cui

Song

Liu

et al. 2021

Foods

Self Cite

View full text Add to dashboard Cite

The potential biological effects of food-borne carbon dots (FCDs) generated during food heating procedures on human health has received great attention. The FCDs will be inevitably exposed to blood proteins along with our daily diet to produce unknown biological effects. In this study, the interaction between FCDs extracted from grilled Spanish mackerel and three main types of human plasma proteins including human serum albumin (HSA), human γ-globulin (HGG) and human fibrinogen (HF) was reported. It was found that the grilled Spanish mackerel FCDs could affect the morphology, size and surface electrical properties of the three proteins. The interaction between the FCDs and proteins had different effects on the secondary structure of the three proteins through a static mechanism. The tested HSA, HGG, and HF could adsorb FCDs to reach saturation state within 0.5 min after the adsorption happened. The binding affinity of the FCDs to the plasma proteins was sorted as follows: HF > HGG > HSA. The results of FCDs interacted with plasma proteins provided useful information in the assessment of the safety of FCDs in our daily diet.

show abstract

Section: Introductionmentioning

confidence: 99%

Interaction of Carbon Dots from Grilled Spanish Mackerel with Human Serum Albumin, γ-Globulin and Fibrinogen

Cui

Song

Liu

et al. 2021

Foods

Self Cite

View full text Add to dashboard Cite

show abstract

“…Furthermore, the bonds at 1620 and 3390 cm −1 were assigned to N-H stretches [25]. The FT-IR results consisted of the previous observation [25] and demonstrated that the magnetic beads had been successfully modified with amino groups. The amino group of magnetic beads could be conjugated with bio-active molecules by glutaraldehyde via Schiff base reaction.…”

Section: Characterization Of Magnetic Probes For CD 2+ Detectionmentioning

confidence: 56%

A Highly Sensitive “on-off” Time-Resolved Phosphorescence Sensor Based on Aptamer Functionalized Magnetite Nanoparticles for Cadmium Detection in Food Samples

Lai

Wang

et al. 2020

Foods

Self Cite

View full text Add to dashboard Cite

Cadmium contamination is a severe threat to food safety. Therefore, the development of sensitive and selective cadmium detection strategies is urgently required. The elimination of background autofluorescence generated from the food matrix is critical to the optical assay for cadmium detection. Herein, a time-resolved phosphorescence sensor based on an “on-off” strategy was developed for cadmium determination in food samples. The phosphorescence nanoparticles were used as a luminous material to minimize the interference of background autofluorescence. The cadmium-binding aptamer was immobilized onto the magnetic beads and combined with a black hole quencher 1 (BHQ1) with complementary DNA as the target recognition element. With the presence of cadmium, the cadmium-binding aptamer bound to cadmium specifically and resulted in the release of BHQ1. The free BHQ1 remained in the solution after magnetic separation and quenched the phosphorescence. The phosphorescence intensity was negatively related to the concentration of cadmium. Under optimal conditions, the time-resolved phosphorescence sensor showed a linear response to cadmium concentration within a range from 0.05 to 5 ng mL−1 and with a detection limit of 0.04 ng mL−1. This “on-off” time-resolved phosphorescence sensor was successfully applied for cadmium detection in spring water and clam samples, which provided a rapid and straightforward method.

show abstract

“…Carbon dots in blood circulation may cause adverse effects and may chronically accumulate in various organs, posing potential risks to human safety. [ 96 ] Long‐term retention of CNTs in bodies may cause delayed toxicity and metastasis of tumors. [ 97 ] Thus, conductive biomaterials should be designed to minimize their possible negative effects on the human body.…”

Section: Biophysical Cues Of Biomaterials For Regulating Stem Cell Behaviormentioning

confidence: 99%

Manipulation of Stem Cells Fates: The Master and Multifaceted Roles of Biophysical Cues of Biomaterials

Wan

Liu

2021

Adv Funct Materials

View full text Add to dashboard Cite

Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing injured tissues, making them a promising source of seed cells for tissue engineering. The extracellular microenvironment (ECM) is under dynamic mechanical control, which is closely related to stem cell behaviors. During the design and fabrication of biomaterials for regenerative medicine, the physiochemical properties of the natural ECM should be closely mimicked, which can reinforce stem cell lineage choice and tissue engineering. By reproducing the biophysical stimulations that stem cells may experience in vivo, many studies have highlighted the key role of biophysical cues in regulation of cell fate. Optimization of biophysical factors leads to desirable stem cell functions, which can maximize the effectiveness of regenerative treatment. In this review, the main biophysical cues of biomaterials, including stiffness, topography, mechanical force, and external physical fields are summarized, and their individual and synergistic influence on stem cell behavior is discussed. Subsequently, the current progress in tissue regeneration using biomaterials is presented, which directs the design and fabrication of functional biomaterial. The mechanisms via which biophysical cues activate cellular responses are also analyzed. Finally, the challenges in basic research as well as for clinical translation in this field are discussed.

show abstract

Endogenous Fluorescence Carbon Dots Derived from Food Items

Cited by 48 publications

References 121 publications

Interaction of Carbon Dots from Grilled Spanish Mackerel with Human Serum Albumin, γ-Globulin and Fibrinogen

Interaction of Carbon Dots from Grilled Spanish Mackerel with Human Serum Albumin, γ-Globulin and Fibrinogen

A Highly Sensitive “on-off” Time-Resolved Phosphorescence Sensor Based on Aptamer Functionalized Magnetite Nanoparticles for Cadmium Detection in Food Samples

Manipulation of Stem Cells Fates: The Master and Multifaceted Roles of Biophysical Cues of Biomaterials

Contact Info

Product

Resources

About