Endogenous Factors Regulating Mosquito Host‐Seeking Behaviour

Klowden, Marc J.

doi:10.1002/9780470514948.ch16

Cited by 23 publications

(22 citation statements)

References 56 publications

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“…Experiments using blood-feeding insects reared under identical laboratory conditions can control for factors such as physiological status, which might influence host-seeking behaviour [26]. However, for N. neivai , as for many other species of sandfly, laboratory rearing is difficult to maintain over more than a few generations [27], with the small number of insects produced being a limiting factor in conducting behavioural studies.…”

Section: Discussionmentioning

confidence: 99%

Attraction of the cutaneous leishmaniasis vector Nyssomyia neivai (Diptera: Psychodidae) to host odour components in a wind tunnel

Pinto¹,

Bray

Eiras

et al. 2012

Parasites Vectors

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BackgroundLaboratory studies of host-seeking olfactory behaviour in sandflies have largely been restricted to the American visceral leishmaniasis vector Lutzomyia longipalpis. In comparison, almost nothing is known about the chemical ecology of related species, which transmit American cutaneous leishmaniasis (ACL), due in part to difficulties in raising these insects in the laboratory. Understanding how ACL vectors locate their hosts will be essential to developing new vector control strategies to combat this debilitating disease.MethodsThis study examined host-odour seeking behaviour of the ACL vector Nyssomyia neivai (Pinto) (=Lutzomyia neivai) using a wind tunnel olfactometer. The primary aim was to determine whether field-collected female N. neivai would respond to host odours in the laboratory, thereby eliminating the need to maintain colonies of these insects for behavioural experiments. Responses to two key host odour components, 1-octen-3-ol and lactic acid, and a commercially-available mosquito lure (BG-Lure™) were assessed and compared relative to an air control. We also tested whether trials could be conducted outside of the normal evening activity period of N. neivai without impacting on fly behaviour, and whether the same flies could be used to assess baseline responses to air without affecting responses to octenol, thereby reducing the number of flies required for experiments.ResultsOctenol was found to both activate host-seeking behaviour and attract female N. neivai in the wind tunnel, while lactic acid elicited weaker responses of activation and attractiveness under identical conditions. The BG-Lure did not activate or attract N. neivai under test conditions. Further experiments showed that sandfly behaviour in the wind tunnel was not affected by time of day, such that experiments need not be restricted to nocturnal hours. Moreover, using the same flies to measure both baseline responses to air and attraction to test compounds did not affect odour-seeking behaviour.ConclusionsThe results of this study demonstrate that N. neivai taken from the field are suitable for use in laboratory olfactometer experiments. It is hoped this work will facilitate further research into chemical ecology of this species, and other ACL vectors.

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Section: Discussionmentioning

confidence: 99%

Attraction of the cutaneous leishmaniasis vector Nyssomyia neivai (Diptera: Psychodidae) to host odour components in a wind tunnel

Pinto¹,

Bray

Eiras

et al. 2012

Parasites Vectors

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“…For instance, the combination of blood-feeding and mating in female mosquitoes has been shown to induce release of peptides (eg, Ae. aegypti Head Peptide I (Aea-HP-I), and short neuropeptide F (sNPF)) that regulates host-attraction and inhibits peripheral olfactory neurons that respond to host odors [57-58]. Yet, the mechanisms by which these neurohormones influence the processing of host information and learning in the brain remains unclear.…”

Section: Figurementioning

confidence: 99%

Learning and Memory in Disease Vector Insects

Vinauger

Lahondère

Cohuet

et al. 2016

Trends in Parasitology

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Learning and memory plays an important role in host preference and parasite transmission by disease vector insects. Historically there has been a dearth of standardized protocols that permit testing their learning abilities, thus limiting discussion on the potential epidemiological consequences of learning and memory to a largely speculative extent. However, with increasing evidence that individual experience and associative learning can affect processes such as oviposition site selection and host preference, it is timely to review the recently acquired knowledge, identify research gaps and discuss the implication of learning in disease vector insects in perspective with control strategies.

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“…Activity reduction associated with MAG injection suggests that females interpreted the injected materials as a signal of insemination. Previous studies suggest that inseminated Aedes females show changes in their activity patterns, because MAGs produce several specific proteins that are transferred to females during mating, influencing reproductive and feeding behaviour ( Klowden 1996 , 1999, Gillott 2003 ). Changes in the pattern of activity of inseminated females have also been described for mosquitoes of other genera, such as Anopheles gambiae ( Jones & Gubbins 1977 , 1978 ) and Anopheles stephensi ( Rowland 1989 ).…”

Section: Discussionmentioning

confidence: 99%

“…Indeed, the AGs of male mosquitoes may produce substances that are transferred to females during mating and alter their physiology and behaviour. The effects of such substances include the inhibition of female remating, stimulation of oviposition and preoviposition behaviours and the inhibition of host-seeking behaviour ( Klowden 1996 , 1999).…”

mentioning

confidence: 99%

Male accessory gland substances from Aedes albopictus affect the locomotor activity of Aedes aegypti females

Lima-Camara¹,

Codeço²,

Honório

et al. 2013

Mem. Inst. Oswaldo Cruz

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Dengue is one of the world’s most important mosquito-borne diseases and is usually transmitted by one of two vector species: Aedes aegypti or Aedes albopictus . These two diurnal mosquitoes are frequently found coexisting in similar habitats, enabling interactions between adults, such as cross-mating. The objective of this study was to assess cross-mating between Ae. aegypti females and Ae. albopictus males under artificial conditions and evaluate the locomotor activity of Ae. aegypti virgin females injected with male accessory gland (MAG) homogenates to infer the physiological and behavioural responses to interspecific mating. After seven days of exposure, 3.3-16% of Ae. aegypti females mated with Ae. albopictus males. Virgin Ae. aegypti females injected with conspecific and heterospecific MAGs showed a general decrease in locomotor activity compared to controls and were refractory to mating with conspecific males. The reduction in diurnal locomotor activity induced by injections of conspecific or heterospecific MAGs is consistent with regulation of female reproductive activities by male substances, which are capable of sterilising female Ae. aegypti through satyrisation by Ae. albopictus .

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Endogenous Factors Regulating Mosquito Host‐Seeking Behaviour

Cited by 23 publications

References 56 publications

Attraction of the cutaneous leishmaniasis vector Nyssomyia neivai (Diptera: Psychodidae) to host odour components in a wind tunnel

Attraction of the cutaneous leishmaniasis vector Nyssomyia neivai (Diptera: Psychodidae) to host odour components in a wind tunnel

Learning and Memory in Disease Vector Insects

Male accessory gland substances from Aedes albopictus affect the locomotor activity of Aedes aegypti females

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