Endogenous Endophthalmitis Caused by Salmonella Serotype B in an Immunocompetent 12-Year-Old Child

Rachitskaya, Aleksandra; Flynn, Harry W.; Davis, Janet L.

doi:10.1001/archophthalmol.2011.1862

Cited by 14 publications

(8 citation statements)

References 10 publications

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“…Studies suggest that EE accounts for 2 to 8% of all endophthalmitis. 1,2 A review of EE in 2003 showed that underlying medical conditions predisposed to ocular infection in 56 to 68% of cases including recent hospitalization, diabetes mellitus, urinary tract infection, immunosuppression (associated with underlying malignancy, neutropenia, and HIV (human immunodeficiency virus)), intravenous drug abuse (IVDA), and indwelling catheters. 3,4 In another study in 2012, 90.9% of patients reported a pre-existing condition of which diabetes mellitus was the most common (50%).…”

Section: Introductionmentioning

confidence: 99%

A British Ophthalmological Surveillance Unit Study on metastatic endogenous endophthalmitis

Maling

King

Davies

2018

Eye

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PurposeEndogenous endophthalmitis (EE) is a rare but serious ocular infection caused by the seeding of bacteria into the eye from a source elsewhere in the body. Studies suggest that EE accounts for 2 to 8% of all endophthalmitis.MethodsA prospective observational study was conducted using the British Ophthalmological Surveillance Unit reporting system. Questionnaires were sent to reporting Ophthalmologists in the UK to assess incidence, underlying aetiology, eye findings, management, and final outcomes in endogenous endophthalmitis over a 12-month period within the British Isles.ResultsSixty two cases reported with 48 initial questionnaires returned and 25 6-month follow-up questionnaires returned. The median age of patients affected was 57 years with youngest aged 2 years and oldest aged 85 years. Twenty three were male and 24 were female. The median visual acuity in the affected eye was 3 logMAR (range -0.1 to 5). Blood cultures were taken in 36 patients, 58% of which were positive. Vitreous biopsy was taken in 35 patients, 23% of which were culture positive. The visual function as assessed by visual acuity had significantly improved at 6 months with a median acuity of 0.18 logMAR (P=0.003).ConclusionsThe survey demonstrates the severe nature of endogenous endophthalmitis in patients with active infection or with risk factors for infection. Our study has demonstrated that at least half of the patients who were treated had significant vision improvement.

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Section: Introductionmentioning

confidence: 99%

A British Ophthalmological Surveillance Unit Study on metastatic endogenous endophthalmitis

Maling

King

Davies

2018

Eye

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“…Studies have shown that endogenous endophthalmitis accounts for 2% to 8% of all endophthalmitis cases[1,2]. It is even rarer in children, and constitutes only 0.1% to 4% of all endogenous endophthalmitis cases[2,3]. In children it may masquerade as uveitis, pre septal orbital cellulitis, congenital glaucoma, conjunctivitis or retinoblastoma.…”

Section: Introductionmentioning

confidence: 99%

Clinical profile and outcomes of pediatric endogenous endophthalmitis: A report of 11 cases from South India

Murugan

Shah

Narendran

2016

WJCP

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AIMTo study the clinical profile and outcomes of pediatric endogenous endophthalmitis from a tertiary eye hospital in South India.METHODSA total of 13 eyes of 11 children presented to us with varied symptoms and presentations of endogenous endophthalmitis, over a five-year period from January 2010 to December 2015 were studied. Except for two eyes of a patient, vitreous aspirates were cultured from all 11 eyes to isolate the causative organism. These eleven eyes also received intravitreal injections. All patients were treated with systemic antibiotics.RESULTSTwo cases had bilateral endophthalmitis. Ages ranged from 4 d to 11 years. Five cases were undiagnosed and treated, before being referred to our center. Ten of the 13 eyes underwent a core vitrectomy. The vitrectomy was done at an average on the second day after presenting (range 0-20 d). Five of the 11 vitreous aspirates showed isolates. The incriminating organisms were bacteria in three and fungus in two. An underlying predisposing factor was found in seven patients. At a mean follow-up 21.5 mo, outcome was good in 7 eyes of 6 cases (54%), five eyes of four cases (38%) ended up with phthisis bulbi while one child died of systemic complications.CONCLUSIONEndogenous endophthalmitis is a challenge for ophthalmologists. Early diagnosis and intervention is the key for a better outcome.

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“…Hersing and Duke-Elders [1] reported typhoid-related uveal complications including iritis, retinal hemorrhage, choroiditis, endophthalmitis and panophthalmitis. Our group published [2],[3] late-onset endogenous endophthalmitis post typhoid fever resolution. In this manuscript we report a patient who presented with retinitis and had a history of typhoid fever, beginning 6 weeks prior to presentation.…”

Section: Introductionmentioning

confidence: 99%

A case of vasculitis, retinitis and macular neurosensory detachment presenting post typhoid fever

Relhan

Pathengay

Albini

et al. 2014

J Ophthal Inflamm Infect

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BackgroundOcular and extraocular immune-mediated phenomena are known to occur following febrile illness. Vasculitis, retinitis and neurosensory detachment are not well-recognized sequelae of typhoid fever.FindingsWe report a case of vasculitis, retinitis and macular neurosensory detachment presenting post typhoid fever. A 27-year-old female presented with decreased vision in right eye with history of typhoid fever (treated adequately 6 weeks prior). Her best corrected visual acuity in right eye was 20/125, N36. Fundus showed a patch of vasculitis and retinitis superior to the disc associated with macular neurosensory detachment and disc pallor. With oral steroids, the inflammation resolved and visual acuity improved to 20/20 at 6 weeks.ConclusionsImmune-mediated vasculitis and retinitis following typhoid fever may respond well to systemic steroids.

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Endogenous Endophthalmitis Caused by Salmonella Serotype B in an Immunocompetent 12-Year-Old Child

Cited by 14 publications

References 10 publications

A British Ophthalmological Surveillance Unit Study on metastatic endogenous endophthalmitis

A British Ophthalmological Surveillance Unit Study on metastatic endogenous endophthalmitis

Clinical profile and outcomes of pediatric endogenous endophthalmitis: A report of 11 cases from South India

A case of vasculitis, retinitis and macular neurosensory detachment presenting post typhoid fever

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