Endodermal sinus tumor of the maxillary sinus: A case report

Gangopadhyay, Kunal; McArthur, Peter; Martin, Justin M.; Saleem, Muhammad

doi:10.1177/014556139907800512

Cited by 16 publications

(10 citation statements)

References 12 publications

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“…1 The prognosis of patients, especially children with ESTs, is unknown, although there have been reports of successful management by surgery, radiotherapy, and adjuvant chemotherapy (cisplatin, bleomycin, and vinblastine). 10,[16][17][18] Weedon and Musgrave 19 described a female infant who had an YST in the maxillofacial area that was diagnosed at the age of 10 months, and she died 1 month later. Margo et al 14 reported 5 cases of YSTs of the orbit occurring in children 3 months to 4 years old.…”

Section: Discussionmentioning

confidence: 99%

Yolk-Sac Tumor of the Postauricular Region: Case Report and Review of the Literature

Rozbahany

Hasanzadazar

Latifi

et al. 2012

Journal of Oral and Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

Yolk-Sac Tumor of the Postauricular Region: Case Report and Review of the Literature

Rozbahany

Hasanzadazar

Latifi

et al. 2012

Journal of Oral and Maxillofacial Surgery

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“…1 Pseudopapillary pattern is the classical pattern associated with the characteristic ''Schiller Duval'' bodies (arrays of a single row of tumor cells about a blood vessel that in turn being surrounded by a cystic space), although several patterns may exist in various areas within a single tumor. 5 Despite this polymorphic histopathologic appearance, EST consistently shows positive immune reactivity to cytokeratin antibodies on immunohistochemistry. 3 Although not characteristic, certain chromosomal abnormalities (particularly chromosomes 1, 3, and 6) have been described in EST.…”

Section: Discussionmentioning

confidence: 99%

Endodermal sinus tumor of the paranasal sinuses

et al. 2007

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“…Four distinct histopathologic types of EST have been described, namely, pseudopapillary, reticular, polyvesicular vitelline, and solid 1. Pseudopapillary pattern is the classical pattern associated with the characteristic “Schiller Duval” bodies (arrays of a single row of tumor cells about a blood vessel that in turn being surrounded by a cystic space), although several patterns may exist in various areas within a single tumor 5. Despite this polymorphic histopathologic appearance, EST consistently shows positive immune reactivity to cytokeratin antibodies on immunohistochemistry 3.…”

Section: Discussionmentioning

confidence: 99%

Rhabdomyosarcoma: Value of myogenin expression analysis and molecular testing in diagnosing the alveolar subtype

Hostein

Andraud-Fregeville

Guillou

et al. 2004

Cancer

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BACKGROUNDIdentification of the alveolar subtype of rhabdomyosarcoma (ARMS) is important, because the poor prognosis associated with this subtype necessitates a modified therapeutic regimen. At present, ARMS diagnoses are made on the basis of histologic findings and the extent of myogenin immunopositivity. Nonetheless, the absence of an alveolar pattern in the solid variant, the low degree of differentiation in certain embryonal rhabdomyosarcomas (ERMS), and the increasing use of microbiopsy samples make the diagnosis of ARMS somewhat difficult. Two specific translocations have been found in ARMS, and fusion transcripts can be detected by reverse transcriptase–polymerase chain reaction (RT‐PCR) analysis of paraffin‐embedded tissue (PET).METHODSTo assess the value of myogenin staining and molecular testing in the diagnosis of rhabdomyosarcoma, the authors examined 109 rhabdomyosarcoma samples (45 ARMS samples and 64 ERMS samples). Real‐time RT‐PCR analysis of PET was performed in all 109 rhabdomyosarcomas, and RT‐PCR analysis of frozen material was performed in 24 cases.RESULTSPAX fusion transcripts were present in 44 cases (39 ARMS and 5 ERMS) and absent in 52 cases (2 ARMS and 50 ERMS). In 13 cases (4 ARMS and 9 ERMS), the results were not interpretable. Results were concordant between paired frozen and fixed tumor samples. All 35 interpretable ERMS samples that contained < 50% myogenin‐positive cells failed to yield detectable PAX fusion transcripts. Of the 61 interpretable tumor samples (41 ARMS and 20 ERMS) that contained > 50% myogenin‐positive cells, 44 (39 ARMS and 5 ERMS) yielded detectable PAX fusion transcripts.CONCLUSIONSThe current study demonstrates that molecular detection of PAX fusion transcripts via real‐time RT‐PCR analysis of PET is a sensitive and specific method for the diagnosis of ARMS and that immunohistochemical analysis of myogenin expression can be used to select cases for such molecular testing. Although RT‐PCR analysis appears not to possess diagnostic value in tumors with < 50% tumor cell immunopositivity, it is strongly recommended for the diagnosis of tumors containing > 50% myogenin‐positive cells. Cancer 2004. © 2004 American Cancer Society.

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Endodermal sinus tumor of the maxillary sinus: A case report

Cited by 16 publications

References 12 publications

Yolk-Sac Tumor of the Postauricular Region: Case Report and Review of the Literature

Yolk-Sac Tumor of the Postauricular Region: Case Report and Review of the Literature

Endodermal sinus tumor of the paranasal sinuses

Rhabdomyosarcoma: Value of myogenin expression analysis and molecular testing in diagnosing the alveolar subtype

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