Endocrine Pancreatic Secretion in Patients After Acute Pancreatitis

Stastná, R; Karasová, L; Svácek, J; Petrásek, R; Winkler, Lina; Lánská, Vilma; Skála, I; Malý, Jan

doi:10.1097/00006676-199005000-00018

Cited by 5 publications

(2 citation statements)

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“…With respect to endocrine function at 6 months following AP, the results of our series showed an improvement because of the decrease in the percentage of DM patients; no relation between endocrine function changes and the severity of AP was found. These results are consistent with others previously reported [33][34][35][36] that noted hyperglycemia to be often transient, with glucose tolerance progressively becoming normal after an AP episode. In general, the reported studies showed that 1 year after an AP episode functional changes can be considered permanent because after this time recovery of normal pancreatic functioning is uncommon [9 -12, 14, 30].…”

Section: Discussionsupporting

confidence: 93%

Pancreatic Function after Acute Biliary Pancreatitis: Does It Change?

et al. 2002

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According to the Cambridge and Marseilles symposia, morphologic and functional recovery from acute biliary pancreatitis (ABP) occurs if the initial cause and complications are eradicated. Nevertheless, in recent years there has been controversy over this topic, and varying results have been reported. These differing results may be due to different diagnostic methods, number of patients studied with regard to etiologic factors, severity of the disease, and differences in the tests used. A total of 63 ABP patients [17 male (27%), 46 female (73%); 45 mild, 18 severe] were prospectively studied. All patients underwent cholecystectomy. No patient in this series underwent necrosectomy or pancreatectomy. During the acute phase the severity of the disease was assessed following the Atlanta criteria, and the occurrence and rate of necrosis were determined by dynamic computed tomography. Exocrine and endocrine pancreatic functions were assessed at 1 month, 6 months, and 1 year after the ABP episode by means of various pancreatic function tests. We evaluated the occurrence of pancreatic failure following ABP and if this deficiency was associated with the severity of the episode. According to the classic symposia criteria, the study showed no deficit in exocrine or endocrine pancreatic function. No statistically significant differences were found when the pancreatic function and severity of the process were assessed.

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Section: Discussionsupporting

confidence: 93%

Pancreatic Function after Acute Biliary Pancreatitis: Does It Change?

et al. 2002

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“…Normal response to glucose has been reported after recovery from an attack of acute alcohol-induced pancreatitis, and is often linked with increased insulin secretion, compared to normal subjects [28] . Regarding alcohol-induced CP (ACP), a long-term clinicomorphological study was conducted concerning 73 patients who were followed up for a mean of 12 years and for whom either surgical or postmortem specimens of the pancreas were available [12] .…”

Section: Progression Of Exocrine and Endocrine Dysfunction After Acutmentioning

confidence: 99%