Endocrine disruptors on and in fruits and vegetables: Estimation of the potential exposure of the French population

Lee, Alexandre; Bensaada, Souad; Lamothe, Valérie; Lacoste, Melissa; Bennetau-Pelissero, Catherine

doi:10.1016/j.foodchem.2021.131513

Cited by 13 publications

(15 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This period partially covers the COVID-19 pandemic and the diet transition to vegan practices in France [ 27 ]. The present assessment of the exposure to IFs was in line with previous studies [ 2 , 3 ]. In addition, the subpopulation exposed to only low doses of IFs exhibited a median urinary excretion of 0.15 µM.…”

Section: Discussionsupporting

confidence: 85%

“…The inquiries were analyzed and translated into a dietary score. The latter considered the level of PHYTOs in foodstuffs that were documented either in [ 3 ] for IFs in French foodstuffs or by other investigators for ENL-precursors (see Table S1 , and associated references). In those studies, the concentration values were all expressed in µg/100 g of fresh food and in aglycone equivalents.…”

Section: Methodsmentioning

confidence: 99%

“…Sources of estrogenic isoflavones (IF), i.e., genistein (GEN), daidzein (DAI), and glycitein ( Figure 1 A), in the human diet are essentially pulses including alfalfa, clover, and soy. However, nowadays, only soybean is a significant source of IFs in the French diet [ 2 , 3 ]. Conversely, enterolactone (ENL) is produced by the gut flora [ 4 , 5 ] and its precursors were shown to be numerous in the diet.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, while the assessment of IFs intake could simply rely on the determination of soy and “hidden soy” intakes [ 2 , 3 ], ENL-precursors’ intake assessment should consider many plant foodstuffs (see Table S1 , and associated references).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Validation of ELISAs for Isoflavones and Enterolactone for Phytoestrogen Intake Assessment in the French Population

et al. 2023

Self Cite

View full text Add to dashboard Cite

Phytoestrogens are dietary compounds with low estrogenic activity. The two main categories in the French diet are isoflavones from pulses and enterolignans metabolized by the gut flora from various lignans found in fruits, vegetables, grains, and beverages. Isoflavones and lignans have different effects on human physiology and can antagonize each other. Comprehensive lists of phytoestrogen sources were constructed based on measurements and literature data. The 24 h and 48 h dietary recalls were proposed to the volunteers of the ISOLED cohort (NCT03421184). Urine and plasma samples from these volunteers were assayed for genistein, daidzein, equol, and enterolactone. A dietary score was constructed considering the pharmacokinetic characteristics of these compounds. Correlation analyses were applied to fluid concentrations associated with dietary scores. Pearson correlations reached 0.921 (p < 0.001) for urineIF, 0.900 (p < 0.001) for plasmaIF, 0.764 (p < 0.001) for urineENL, and 0.723 (p < 0.001) for plasmaENL. ELISAs associated with careful intake assessments proved to be good tools for phytoestrogens’ exposure estimation.

show abstract

Section: Discussionsupporting

confidence: 85%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Validation of ELISAs for Isoflavones and Enterolactone for Phytoestrogen Intake Assessment in the French Population

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…The main dietary source of isoflavones are legumes from the family Fabaceae ( 97 ), namely soybeans ( Glycine max ). Mean isoflavone intake in Japan among older adults ranges from ~30 to 50 mg/d ( 45 , 98 ) whereas daily per capita intake in the United States ( 99 – 101 ) and Europe ( 102 , 103 ) is <3 mg, although recent reports suggested daily intake may be as high as 7 mg in France ( 104 ) and was estimated at 4–6 mg among British adults although little of that came from soyfoods ( 103 ).…”

Section: Isoflavonesmentioning

confidence: 99%

The health effects of soy: A reference guide for health professionals

Messina¹,

Duncan

Messina

et al. 2022

Front. Nutr.

View full text Add to dashboard Cite

Soy is a hotly debated and widely discussed topic in the field of nutrition. However, health practitioners may be ill-equipped to counsel clients and patients about the use of soyfoods because of the enormous, and often contradictory, amount of research that has been published over the past 30 years. As interest in plant-based diets increases, there will be increased pressure for practitioners to gain a working knowledge of this area. The purpose of this review is to provide concise literature summaries (400–500 words) along with a short perspective on the current state of knowledge of a wide range of topics related to soy, from the cholesterol-lowering effects of soy protein to the impact of isoflavones on breast cancer risk. In addition to the literature summaries, general background information on soyfoods, soy protein, and isoflavones is provided. This analysis can serve as a tool for health professionals to be used when discussing soyfoods with their clients and patients.

show abstract