Endocrine-Disrupting Chemicals (EDCs) and Reproductive Outcomes

Abstract

Endocrine-disrupting chemicals (EDCs) are prevalent throughout the environment and known to negatively impact fertility. As the prevalence of unexplained subfertility increases worldwide, it is important to understand the impact EDCs might have on reproduction and fertility treatments, such as in vitro fertilisation (IVF). This chapter examines the impact of EDCs on assisted reproduction treatments and pregnancy outcomes. The literature is frequently conflicting; however, the association between exposure to EDCs and poor reproductive outcomes is undeniable. Women of a reproductive age should therefore minimise exposure to these chemicals where possible, with healthcare professionals actively advocating their avoidance where possible. Further research is needed to determine the exact mechanisms of action of these substances, to identify which specific chemicals have the greatest effect and to provide recommendations for how to mitigate these effects.