Endocrine Dependence of Rat Seminal Vesicle Tissue in Tissue Culture

The Action of Prolactin on the Sex Accessory Glands of the Male Rat

“…In addition, prolactin synergizes with testosterone to increase the weight of the ventral (4)(5)(6) and dorsolateral prostate (7,8 ) of the rat. The seminal vesicles have also been found to increase in weight in response to prolactin acting either synergistically with testosterone ( 5 , 9, lo), or independently ( 11,12). As a result of the synergism of prolactin and testosterone there is an increase in the fructose and citric acid content of the dorsolateral prostate (7,8 ) , seminal vesicles, and coagulating gland (9).…”

The Combined Effect of Prolactin and Androsterone on the Growth of Rat Seminal Vesicle in vitro

“…Tissue cultures have been made from the seminal vesicle of adult intact Sprague Dawley rats using a technique described in detail in another paper (4). As culture medium plasma from cockerels of about one year of age was used.…”

Synergistic Action of Prolactin With HCG on Rat Ventral Prostate

“…Earlier studies have indicated that prolactin stimulates prostatic growth (Okamoto et al, 1967;Negro-Vilar et al, 1973) and increases the weight of the seminal vesicles (Chase et al, 1957;Antliff et al, 1960;Bengmark & Hesselsjo, 1963, 1964Dorfman, 1972;Negro-Vilar et al, 1973). These effects, however, were manifest only when prolactin was used with androgens.…”

“…Several investigators have claimed that prolactin alone or synergistically with androgens has a role in the growth of the male accessory sex organs (Segaloff et al, 1956;Chase et al, 1957;Antliff et al, 1960;Bengmark & Hesselsjo, 1963, 1964Okamoto et al, 1967;Dorfman, 1972;Negro-Vilar et al, 1973). In these studies, large amounts of prolactin were used, and the possible presence of small amounts of contaminating LH could not be ruled out.…”