Endocellular parasitism of Mycobacterium avium in rabbit liver. A morphological study

Histopathology and Histochemistry of Yersin Type Tuberculosis in Rabbits. Development of the Disease after Intravenous Infection with Mycobacterium avium

“…This was very clearly seen in the liver and spleen where the macrophages proliferation was in the latest stages almost diffuse. This feature of Yersin type tuberculosis described Yamamoto et al (1961Yamamoto et al ( a, b, c, 1962, Cerny (1965), Mohelska et al (1975). This finding was connected with the development of the cells of the macrophage system.…”

“…. In Yersin type tuberculosis 'mycobacteria act evidently as intracellular parasites (Cerny 1965;Mohelska et al 1975). This is known to apply to tuberculosis in other species as well, e. g. in birds (Cerny 1965;HejJicek 1977).…”

Lysosomal Enzyme Content of Kupffer and Endothelial Liver Cells Isolated from Germfree and Clean Conventional Rats

“…The Kupffer and endothelial cells in the sinusoidal areas of the liver may play a central role in the animal's defense against circulating microorganisms and other pathogenic agents (20). The phagocytosis of bacteria and the bactericidal activity of Kupffer cells have already been clearly demonstrated (5)(6)(7)13). Kupffer cells are also almost exclusively responsible for the clearance of bacterial products such as endotoxin (D. P. Praaning-van Dalen, A. Brouwer, and D. L. Knook, submitted for publication).…”