Endocarditis infecciosa por Listeria monocytogenes: revisión de la literatura a partir de un caso clínico

Abstract

Infective endocarditis caused by Listeria monocytogenesis an extremely rare but usually aggressive disease. We have seen in recent years an increase in age of onset of this disease and a predilection for patients with valvular disease, especially prosthetic valve. The treatment of choice is ampicillin, which is combined with gentamicin for synergy. It is known that even with treatment the mortality is very high and higher than in other types of bacterial endocarditis. With optimal therapy, that is medical-surgical, mortality has declined significantly in recent years. We presents a review of the literature and a clinical case of a patient with a febrile syndrome diagnosed as a infective endocarditis caused by L. monocytogenestreated medically with successful outcome to date.

A non-surgical approach: Ampicillin's success in Listeria monocytogenes endocarditis

“…Third-generation cephalosporins exhibit weak activity against LM due to low affinity for PBP 3 [11] . Treatment for prosthetic valve cases is recommended to last a minimum of 6 to 8 weeks [12] .…”

Infective endocarditis due to Listeria monocytogenes: Case treated without surgical intervention with adequate clinical evolution

“…A pesar de los avances médicos, la endocarditis infecciosa (EI) conserva una elevada morbimortalidad (0,87 muertes por cada 100.000 personas de la población) [ 1 ]. Además, sigue siendo un reto diagnóstico debido al amplio abanico de manifestaciones clínicas con las que puede presentarse, ello dependiendo de; edad del paciente [ 2 ], microorganismo causante, y presencia de antecedentes previos como hepatopatía, insuficiencia renal, valvulopatías, et al Todo ello hace que se requiera de colaboración multidisciplinaria para su manejo [ 3 ].…”