Endocardite infectieuse aortopulmonaire d’évolution fatale : à propos d’un cas

Infectious Endocarditis in Sub-Saharan Africa: Epidemic-Clinical Aspects, Evolutionary and Prognostic: Multicentre Study on 81 Cases Followed Over 1 Year in Lomé (Togo)

“…Blood cultures are often negative (71.6%). This high rate of negative blood cultures was also found in the most African series [14][15][16][17][18][19][20]. This can be explained in Africa by antibiotic therapy untimely, poor technical conditions for producing blood cultures (collection, storage and delivery of blood samples), lack of suitable culture media to isolate demanding or slowgrowing germs.…”

“…In developed countries, aortic involvement is most common during endocarditis infection on acquired valve diseases, due in particular to the increase in incidence of degenerative aortic valve disease in the elderly congenital heart disease comes second to underlying heart disease in our study [1][2][3][4][5][6][7][8][9][10][11][12][13]. However, the scarcity of AEs on congenital heart disease was highlighted in several African series [14][15][16][17][18][19][20]. Probably because these studies were done in adult cardiology where congenital heart disease is less frequent.…”

“…In this work the hospital prevalence of infectious endocarditis was 1.3%. Patients with AE are young in Africa, while they are older in western series (mean age 30 vs 60-70) [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Clinical signs were dominated by the combination of fever + heart murmur.…”

“…Nevertheless, this decline does not mean disappearance because these rheumatic heart diseases still continue to be the bed endocarditis. The predominance of mitral damage may be related to the greater frequency of these valvular lesions during rheumatic fever (AAR) [14][15][16][17][18][19][20]. In developed countries, aortic involvement is most common during endocarditis infection on acquired valve diseases, due in particular to the increase in incidence of degenerative aortic valve disease in the elderly congenital heart disease comes second to underlying heart disease in our study [1][2][3][4][5][6][7][8][9][10][11][12][13].…”

“…Infectious endocarditis (AE) remains a serious disease, with an overall mortality of 20 to 30% in the West, despite advances in antibiotic therapy and surgery heart rate [1][2][3][4][5][6][7][8][9][10][11][12][13]. In sub-Saharan Africa, the low socioeconomic level of patients, cultural context, diagnostic delay, antibiotic limits and difficult accessibility of cardiac surgery, make the prognosis of AE quite reserved with significantly higher mortality than in the West [14][15][16][17][18][19][20]. Very few African studies were devoted to the medium and longterm prognosis of AE.…”