Endobronchiale Applikation von Adrenalin in der präklinischen kardiopulmonalen Reanimation

Schüttler, J.; Bartsch, A.; Ebeling, B. J.; Hörnchen, U; Kulka, P. J.; Sühling, B; Stoeckel, H.

doi:10.1055/s-2007-1002512

Cited by 23 publications

(2 citation statements)

References 2 publications

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“…In 2 animal CPR studies the equipotent epinephrine dose given endotracheally was approximately 3 to 10 times higher than the IV dose. 261,262 Providers should dilute the recommended dose in 5 to 10 mL of sterile water or normal saline and inject the drug directly into the endotracheal tube. 256 Studies with epinephrine 263 and lidocaine 251 showed that dilution with sterile water instead of 0.9% saline may achieve better drug absorption.…”

Section: Endotracheal Drug Deliverymentioning

confidence: 99%

Part 8: Adult Advanced Cardiovascular Life Support

Neumar¹,

Otto²,

Link³

et al. 2010

Circulation

1,338

872

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Section: Endotracheal Drug Deliverymentioning

confidence: 99%

Part 8: Adult Advanced Cardiovascular Life Support

Neumar¹,

Otto²,

Link³

et al. 2010

Circulation

1,338

872

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“…. 12,26,27). Es folgt ein Intervall von 2-3 min möglichst effektiver Herzdruckmassage, ohne die wirksame Adre-nalinPlasmaspiege1 am arteriellen Wirkort nicht erreicht werden können (13).…”

Section: Adrenalindosis Und Ozltcorneunclassified

Welches Dosierungskonzept für Adrenalin ist bei kardiopulmonaler Reanimation das richtige? - Eine Datenanalyse präklinischer Reanimationen.

Fischer

Fischer²,

Schüttler³

1995

Anästhesiol Intensivmed Notfallmed Schmerzther

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Based on these data, we recommend an escalating epinephrine dosage concept, which facilitates titration of the drug to an effective level and meets the needs of the individual patient. This concept avoids overdosage in patients who had just collapsed shortly before initiation of CPR, attains higher levels of epinephrine in patients suffering from prolonged cardiac arrest, and takes into consideration that the effective epinephrine dose varies individually and increases with prolongation of the cardiac arrest interval.

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