Endobronchial Lipoma Excision by Cryotherapy and Flexible Bronchoscopy

Largo, Sofia Jaurrieta; Sánchez, Blanca de Vega; Vicente, Carlos Disdier

doi:10.1016/j.arbr.2019.02.009

Cited by 1 publication

(1 citation statement)

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“…It may be a completely solitary tumor or accompanied by pneumonia, atelectasis, aspergillosis, emphysema, and bronchiectasis. 1 , 10 – 13 , 20 , 21 There is no calcification and soft tissue components in this tumor, which is significantly different from that of the fat-containing hamartoma.…”

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confidence: 76%

An unexpected encounter and outcome between endobronchial lipoma and carcinoma: a case report and literature review

Yang,

Liu,

Chen

et al. 2023

Ther Adv Respir Dis

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Bronchial lipoma is a rare benign tumor of the lung, which is often misdiagnosed due to concomitant pulmonary diseases. In addition, the coexistence of endobronchial lipoma and lung cancer is extremely unusual. To date, no related computed tomography (CT) images have been reported. The patient was a 53-year-old man, who was admitted to our hospital with cough, yellow phlegm, and fever for 1 week. The CT image showed an irregular mass in the medial segment of the right middle lobe (B4a) with surrounding ground glass opacity, and another solid nodule in the right lower lobe (B6b). Unfortunately, after 2 weeks of anti-inflammatory treatment, the bronchial invasion of the B4a nodule did not decrease significantly, so further bronchoscopy was carried out and tumor resection was performed using endoscopic mucosal resection with a ligation device (EMR-L). During the follow-up 4 months, it was found that the B6b nodule was marked enlargement and then removed. The lesions of the B4a and B6b were confirmed as endobronchial lipoma and squamous cell carcinoma (T1aN0M0) by histopathology and immunohistochemical staining, respectively, and no postoperative radiotherapy or chemotherapy was performed. Regrettably, after 29 months of follow-up, we observed recurrence and slow enlargement of the lipoma in its original location, progressive emphysema in both lungs, and solitary chest wall metastasis from the B6b squamous cell carcinoma that had been resected. Therefore, endobronchial endoscopy resection should be carefully selected for larger endobronchial lipoma. If it is accompanied by early squamous cell carcinoma (T1aN0M0), we still recommend active postoperative chemoradiotherapy.

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