Endobronchial lipoma, an extremely rare benign tumour of the lung, mimicking asthma bronchiale

Rooijakkers, M.; Wynants, Jokke; Aumann, Joseph-Leon

doi:10.1179/0001551213z.00000000010

Cited by 6 publications

(9 citation statements)

References 3 publications

(16 reference statements)

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“…This type ofwheeze is usually caused by high-velocity airflow through narrow airways. Common causes are intraluminal obstruction by a tumour, secretions, foreign bodies, and external compression to the airway [4][5][6].In this case, the wheeze was heard only on inspiration. Such wheezing is caused by dilatation of the obstructed airway and a partial increase of the air flow velocity on inspiration.…”

Section: Discussionmentioning

confidence: 88%

Endobronchial Lipoma Presenting with Localised Wheezes: A Case Report

Akgedik¹,

Kurt²,

Akgedik³

et al. 2015

Med-Science

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A 67-year-old non-smoking man was referred to our clinic with dry cough and shortness of breath during exercise over the course of 6 months. The physical examination was unremarkable except for the presence of isolated localised wheezes over the left upper lung. His chest X-ray was normal. A computed tomography (CT) scans of chest revealed an irregular and partial obstruction of the left upper lobe bronchus with soft-tissue density lesion. Bronchoscopy revealed the presence of a smooth surface tumour occluding the orifice of the lingula bronchus. The lesion and its stalk were totally removed by cutting with forceps. After the removal of the lesion, patient's dyspnoea and wheezes were disappeared completely. Histopathological examination of the lesion was reported as endobrochial lipoma (EL).At the 2-years follow-up period, the patient was remained asymptomatic. We present a case report of an unusual presentation of EL with localised wheezes and without the presence of fat density on CT scanning.

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Section: Discussionmentioning

confidence: 88%

Endobronchial Lipoma Presenting with Localised Wheezes: A Case Report

Akgedik¹,

Kurt²,

Akgedik³

et al. 2015

Med-Science

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“… 7 , 8 Endobronchial lipomas occur predominately in men aged 50–80 years old, but rarely in women. 1 – 5 , 7 – 10 Clinical symptoms in the vast majority of patients include cough, expectoration, hemoptysis, asthma, fever, and dyspnea, but there is no typical symptom. 1 , 9 , 10 It is well known that smoking and obesity are risk factors, but neither of these factors is found in our patient.…”

Section: Discussionmentioning

confidence: 99%

“… 1 – 5 , 7 – 10 Clinical symptoms in the vast majority of patients include cough, expectoration, hemoptysis, asthma, fever, and dyspnea, but there is no typical symptom. 1 , 9 , 10 It is well known that smoking and obesity are risk factors, but neither of these factors is found in our patient. 9 However, our patient had a history of hypertension and diabetes, which has also been reported in three articles.…”

Section: Discussionmentioning

confidence: 99%

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An unexpected encounter and outcome between endobronchial lipoma and carcinoma: a case report and literature review

Yang,

Liu,

Chen

et al. 2023

Ther Adv Respir Dis

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Bronchial lipoma is a rare benign tumor of the lung, which is often misdiagnosed due to concomitant pulmonary diseases. In addition, the coexistence of endobronchial lipoma and lung cancer is extremely unusual. To date, no related computed tomography (CT) images have been reported. The patient was a 53-year-old man, who was admitted to our hospital with cough, yellow phlegm, and fever for 1 week. The CT image showed an irregular mass in the medial segment of the right middle lobe (B4a) with surrounding ground glass opacity, and another solid nodule in the right lower lobe (B6b). Unfortunately, after 2 weeks of anti-inflammatory treatment, the bronchial invasion of the B4a nodule did not decrease significantly, so further bronchoscopy was carried out and tumor resection was performed using endoscopic mucosal resection with a ligation device (EMR-L). During the follow-up 4 months, it was found that the B6b nodule was marked enlargement and then removed. The lesions of the B4a and B6b were confirmed as endobronchial lipoma and squamous cell carcinoma (T1aN0M0) by histopathology and immunohistochemical staining, respectively, and no postoperative radiotherapy or chemotherapy was performed. Regrettably, after 29 months of follow-up, we observed recurrence and slow enlargement of the lipoma in its original location, progressive emphysema in both lungs, and solitary chest wall metastasis from the B6b squamous cell carcinoma that had been resected. Therefore, endobronchial endoscopy resection should be carefully selected for larger endobronchial lipoma. If it is accompanied by early squamous cell carcinoma (T1aN0M0), we still recommend active postoperative chemoradiotherapy.

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“…Endobronchial lipomas, which are rare benign tumors of the lung, can likewise present with asthma-like wheezing. 14 In addition, endobronchial tuberculosis presenting as a polypoid, necrotic endobronchial lesion has been reported to produce symptoms mimicking asthma. 15 …”

Section: Discussionmentioning

confidence: 99%

Asthma mimic: Case report and literature review of vocal cord nodule associated with wheezing

Kashif

Singh

Aslam

et al. 2017

SAGE Open Medical Case Reports

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Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. Various clinical conditions can mimic asthma, such as foreign body aspiration, subglottic stenosis, congestive heart failure, diffuse panbronchiolitis, aortic arch anomalies, reactive airway dysfunction syndrome, chronic obstructive pulmonary disease, retrosternal goiter, vocal cord tumors, other airway tumors, and vocal cord dysfunction. Upper airway obstruction can be a life-threatening emergency. Here, we present the case of a 58-year-old female with recurrent hospital visits for wheezing and exacerbations of asthma, who was later found to have a vocal cord nodule confirmed to be squamous cell carcinoma, which was mimicking like asthma.

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Endobronchial lipoma, an extremely rare benign tumour of the lung, mimicking asthma bronchiale

Cited by 6 publications

References 3 publications

Endobronchial Lipoma Presenting with Localised Wheezes: A Case Report

Endobronchial Lipoma Presenting with Localised Wheezes: A Case Report

An unexpected encounter and outcome between endobronchial lipoma and carcinoma: a case report and literature review

Asthma mimic: Case report and literature review of vocal cord nodule associated with wheezing

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