Endobronchial Cryotherapy

Maiwand, M.; Mathur, Praveen N.

doi:10.1055/s-2007-1009370

Cited by 8 publications

(7 citation statements)

References 37 publications

(49 reference statements)

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“…Ettinger, has suggested that decreasing the tumor burden prior to surgery may inhibit metastases and minimize the drug resistance for intravenous chemotherapy [86]. Indeed, the clinical studies on the subject of neoadjuvant intratumoral cryotherapy prior to the surgery in lung cancer [87], and early prostate cancer [88,89], have demonstrated that relapse with metastases occurs much less often in patients treated preoperatively with intratumoral cryotherapy.…”

Section: Asymptomatic Lesions With Less Than 50% Obstruction Of Majormentioning

confidence: 99%

Bronchoscopic intratumoral chemotherapy of lung cancer

2008

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Section: Asymptomatic Lesions With Less Than 50% Obstruction Of Majormentioning

confidence: 99%

Bronchoscopic intratumoral chemotherapy of lung cancer

2008

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“…Effective killing zone is 5 to 8 mm. 10,11 Tissues with higher water content, such as skin, granulation tissue, mucous membrane, nerve, endothelium, tumor tissue are cryosensitive, whereas cartilage, connective tissue, fibrous tissue, fat, and nerve sheaths are cryoresistant. 12 …”

Section: Vascular Injurymentioning

confidence: 99%

Cryotechnology in Diagnosing and Treating Lung Diseases

Tomic

Podgaetz

Andrade

et al. 2015

Journal of Bronchology &Amp; Interventional Pulmonology

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Cryotechnology has been used in treating lung cancer for many years, now it is emerging to have a new indication in diagnosing lung diseases. Cryoprobe transbronchial lung biopsy has been introduced into clinical practice as a new technique, providing a larger biopsy specimen, potentially improving the diagnostic yield of transbronchial biopsies in parenchymal lung diseases. Although recent small pilot studies suggest that cryotransbronchial lung biopsies are comparable to conventional transbronchial biopsies in terms of diagnostic yield and safety profile in lung transplant patients, cryoprobe transbronchial lung biopsy is still being evaluated and its role in clinical practice is not well defined. Cryotherapy has been proven as a safe and effective method to debulk endobronchial lesions, providing palliation for advanced central obstructive tumors. Its use and efficacy is also studied in direct cryosurgery and percutaneous application in lung cancer. Cryoprobes can also be used to extract foreign bodies from the airways by causing cryoadhesion. We aim to summarize the therapeutic and diagnostic application of cryotechnology in pulmonary diseases.

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“…Cryotherapy is a safe and effective tool for many airway problems 28,29 . The device releases nitrous oxide or carbon dioxide stored under pressure into the tip of the cryoprobe and rapidly cools to −89°C to destroy tissue and tumour.…”

Section: Use Of Cryotherapy Percutaneously and Within The Central Airmentioning

confidence: 99%

“…Cryotherapy is a safe and effective tool for many airway problems. 28,29 The device releases nitrous oxide or carbon dioxide stored under pressure into the tip of the cryoprobe and rapidly cools to -89°C to destroy tissue and tumour. The effectiveness of cryotherapy depends on the rapidity of the freezing and thawing process, the lowest temperature achieved, the number of freeze-thaw cycles and the water content of the tissue.…”

Section: Use Of Cryotherapy Percutaneously and Within The Central Airmentioning

confidence: 99%

Emerging technologies for the thorax: Indications, management and complications

2010

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The field of interventional pulmonology has rapidly expanded to include the management and treatment of complex diseases of the chest. The management of central airway obstruction, pleural disease diagnosis, treatment and palliation, advanced bronchoscopic techniques to aid in the diagnosis of lung cancer and innovative therapies to treat asthma and COPD have all emerged over the past decade. As astute clinicians, we are all aware of the risks and benefits of using these therapies to treat our patients. In order to appropriately treat and manage these often complex medical situations, the physician should have an expert knowledge of all available modalities, the expertise to safely perform the procedure and the ability to minimize the risk of and manage the associated complications that may arise. In this chapter we review and update some of the bronchoscopic and pleural interventions offered by interventional pulmonologists as well as the associated complications and management.

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Endobronchial Cryotherapy

Cited by 8 publications

References 37 publications

Bronchoscopic intratumoral chemotherapy of lung cancer

Bronchoscopic intratumoral chemotherapy of lung cancer

Cryotechnology in Diagnosing and Treating Lung Diseases

Emerging technologies for the thorax: Indications, management and complications

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