Endemic skeletal fluorosis

Teotia, M; Teotia, S. P. S.; Kunwar, K. B.

doi:10.1136/adc.46.249.686

Cited by 59 publications

(21 citation statements)

References 8 publications

(7 reference statements)

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“…Though skeletal fluorosis in adults has been observed in many parts of India, and from other areas such as South Africa, China and the Persian Gulf, reports of skeletal fluorosis in children are few (Teotia et al, 1971). Teotia et al (1971) reported six cases of skeletal fluorosis in children aged 6-14 years, resident in high fluoride areas (10.35-13.5 j.lg F/rnl).…”

Section: Safe and Optimal Levels Of Fluoride Ingestionmentioning

confidence: 99%

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Fluoride Intake of Infants in New Zealand

1990

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Section: Safe and Optimal Levels Of Fluoride Ingestionmentioning

confidence: 99%

“…Teotia et al (1971) reported six cases of skeletal fluorosis in children aged 6-14 years, resident in high fluoride areas (10.35-13.5 j.lg F/rnl). Of the six affected patients, five were males.…”

Section: Safe and Optimal Levels Of Fluoride Ingestionmentioning

confidence: 99%

Fluoride Intake of Infants in New Zealand

1990

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“…Skeletal pathologies include abnormal bone formations on the appendicular or axial skeleton, mostly linked with the insertions of tendons and ligaments [11]. In clinically diagnosed cases of fluorosis in children, skeletal manifestations included osteopenia, growth lines, and sclerosis [105][106][107]. Considering that there is no widespread dental staining nor skeletal lesions relating to fluorosis, it is unlikely that B70 suffered from fluorosis.…”

Section: Differential Diagnosismentioning

confidence: 99%

Diagnosis of Mercurial Teeth in a Possible Case of Congenital Syphilis and Tuberculosis in a 19th Century Child Skeleton

Ioannou

Henneberg

et al. 2015

Journal of Anthropology

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Without the presence of “caries sicca,” “sabre shins,” and nodes/expansion of the long bones with superficial cavitation, differential diagnosis of venereal syphilis and tuberculosis (TB) may be difficult as various infections produce similar responses. However, congenital syphilis has distinctive features facilitating a diagnosis. A case study of remains of a juvenile European settler (probably male, 8–10 years old) (B70) buried in the 19th century and excavated in 2000 from the cemetery of the Anglican Church of St. Marys in South Australia is presented. B70 demonstrated that the two diseases might have been present in the same individual, congenital syphilis and TB. Widespread destruction of vertebral bodies and kyphosis-related rib deformations indicate advanced TB. Severe dental hypoplasia is limited to permanent incisors and first molars; there is pitting on the palate, periosteal reaction on the skull vault, and thinned clavicles. Dental signs are not limited to “screwdriver” central incisors and mulberry molars. Apical portions of the crowns of permanent upper, lower, central, and lateral incisors have multiple hypoplastic-disorganized defects; deciduous canines have severely hypoplastic crowns while possibly hypoplastic occlusal surfaces of lower deciduous second molars are largely destroyed by extensive caries. These dental abnormalities resemble teeth affected by mercurial treatment in congenital syphilitic patients as described by Hutchinson.

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“…Cohen et al [40] have suggested that the magnesium malabsorption found in 12 of 20 of their osteoporotic patients may account for this magnesium deficiency state [40], Lowered bone magnesium content has been reported in diabetes [32,36] and in otosclerotic bone [41]. Increased magnesium levels have been reported in human fluorotic bone [42,43] and in quail [44] and chick [45,46] studies. However, when fluoride-supplemented animals are placed on a low-magnesium diet, bone magnesium de creased [47], Early work by Pellegrino and Biltz [48] showed no difference in magnesium content between control sub jects and patients with renal disease of less than 2 or more than 2 years.…”

Section: Magnesium and Bone Diseasementioning

confidence: 98%