Encouraging results for the Contegra conduit in the problematic right ventricle–to–pulmonary artery connection

Abstract

At midterm follow-up, the Contegra conduit remains a reliable, accessible, and easily implantable conduit for right ventricular outflow tract reconstruction. It appears to be the most promising conduit option for patients with previous homograft conduits and for infants.

Infective Endocarditis After Transcatheter Pulmonary Valve Replacement Using the Melody Valve

“…Similarly, Despite the limited data on IE after RVOT conduit or valve surgery, this complication has been reported with most of the surgical RVOT prostheses that are used. [24][25][26][27][28][29][30][31][32][33] Judging by the available literature, including studies other than those in Table 3 that report no cases of IE, 35,36 the rate of IE in Contegra conduits is not substantially different than in other types of surgical pulmonary valve or conduit. In a recent case series of IE after Melody valve implant, Patel et al 15 speculated that, "inherent biological characteristics of the Contegra valve and its method of preparation maybe contributing to the thrombogenicity and possible tropism for microorganisms."…”

O conduto valvulado bovino contegra, um biomaterial para o tratamento cirúrgico de cardiopatias congênitas

“…The mean conduit sizes were 14-20.4 mm from different reports 16,17,20,31,32,35 ( Figure 2). The median sizes were reported to be 16 mm 19 , and 20 mm 35 . Graft size ≤ 20 mm was utilized in 51.8% of the patients 35 .…”

“…Conduit plasty was necessary in 6 (0.4%), and reintervention to the conduit or to the pulmonary arteries in 83 (4.9%) patients. The conduit reimplantation was due to severe stenosis (excessive gradient) of the distal anastomosis refractory to interventional treatment 9,14,24,33,35 , (pseudo)aneurysm of the proximal anastomosis 19 , progressive right ventricular dysfunction caused by severe conduit regurgitation 18,20,33 , endocarditis 11,35 or graft degeneration 35 .…”

Valved Conduits Right Ventricle to Pulmonary Artery for Complex Congenital Heart Defects

“…structural continuity between the wall of the jugular vein of the conduit and the valve leaflets, which provides optimal hemodynamics because of the ideal effective orifice area b. unlimited "off-the-shelf" availability in sizes from 12 to 22 mm diameter, representing a good alternative to the homograft shortage, particularly in the smaller sizes c. availability of a long length at both inflow and outflow that obviates the need for either proximal or distal augmentation; this facilitates conduit tailoring and positioning which helps to avoid potential distortion and sternal compression d. exceptional reports of antigenic reaction, due to glutaraldehyde fixation In contrast to the good clinical results obtained in several institutions (37)(38)(39)(40)(41)(42)(43)(44)(45), a disturbing sequence of publications reported stenosis at the level of the distal anastomosis of the conduit, with proximal conduit dilatation, aneurysm or pseudo-aneurysm, in between 6 and 50% of patients (39,40,42,(46)(47)(48)(49)(50)(51)(52)(53)(54).…”

“…The problem of conduit dilatation related to obstruction at the distal anastomosis has been reported as a specific complication of the bovine jugular vein (46)(47)(48)(49)(50)(51)(52)(53)(54).…”