Encephalomyelitis following mumps

Ünal, Aysun; Emre, Ufuk; Atasoy, H. Tuğrul; Sümer, Murat; Mahmutyazıcıoğlu, Kamran

doi:10.1038/sj.sc.3101735

Cited by 8 publications

(7 citation statements)

References 11 publications

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“…However, serious complications such as orchitis, pancreatitis, meningitis, and encephalitis occasionally occur ( 1 ). At most 10% of all patients with mumps parotitis develop clinical meningitis ( 4 5 ), which may develop without parotid gland swelling, as occurred in the present case. Mumps encephalitis is uncommon in adults ( 3 ), but when it is encountered, impaired consciousness, seizures, and psychological symptoms are often observed; in such cases, serological diagnosis or virus isolation is required for differential diagnosis.…”

Section: Discussionsupporting

confidence: 63%

Magnetic Resonance Imaging Findings of Mumps Meningoencephalitis with Bilateral Hippocampal Lesions without Preceding Acute Parotitis: A Case Report

et al. 2017

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Meningitis is a common central nervous system (CNS) complication of the mumps, a viral infection, but encephalitis and meningoencephalitis are less common in mumps. We describe magnetic resonance imaging findings of acute mumps meningoencephalitis in a 32-year-old male who showed bilateral hippocampal lesions without preceding parotitis. Although it is rare, hippocampal involvement should be considered a CNS complication of mumps infection.

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Section: Discussionsupporting

confidence: 63%

Magnetic Resonance Imaging Findings of Mumps Meningoencephalitis with Bilateral Hippocampal Lesions without Preceding Acute Parotitis: A Case Report

et al. 2017

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“…4,5 The present case differs from these reports in that our patient presented with only paraparesis and urinary difficulty due to acute LETM. In addition, his recovery from the neurological impairment was considerably faster than has been reported previously.…”

Section: Discussioncontrasting

confidence: 54%

“…Most of the cases had a slow recovery from the myelitis. 3,4 Here we report a boy who presented with paraparesis and urinary retention due to an LETM as a rare neurological complication after mumps infection. …”

mentioning

confidence: 99%

Multifocal Longitudinally Extensive Transverse Myelitis as a Rare Complication of Mumps Infection

Ahn

Kim

Bae

et al. 2018

J Neurosonol Neuroimag

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Myelitis is one of the rare neurological complications of mumps infection. However, there have been few reports of multifocal longitudinally extensive transverse myelitis (LETM) as a complication during the convalescent stage after acute mumps infections. A 14-year-old boy abruptly developed paraplegia, paresthesia of both legs, and urinary retention 4 weeks after acute mumps infection, from which he had recovered with supportive treatment. Spinal magnetic resonance imaging revealed two separate LETMs lesions over the thoracic spinal cord. Other radiological and electrophysiological studies revealed no evidence of demyelinating disorders. The results of laboratory studies were all negative except for evidence of recent mumps infection. He was treated with a high-dose intravenous steroid, and recovered from his neurological symptoms about 1 month later. This is the first report of multifocal LETM after acute mumps infection. LETM is thus not only associated with neuroimmunological syndromes, such as neuromyelitis optica, but it can also develop after acute viral infection. J Neurosonol Neuroimag 2018;10(1):37-40 Key Words: Mumps; Myelitis; Transverse; Complications; Paraplegia Longitudinally extensive transverse myelitis (LETM) is defined as a myelitis that longitudinally extends over at least three serially adjacent vertebral segments. LETM is associated with several conditions, with neuromyelitis optica (NMO) being the most frequent, followed by spinal cord infarction and para-or postinfectious myelopathy, involving various pathogens. 1 Acute mumps infection is known to be associated with various neurological complications, such as aseptic meningitis, acute encephalitis, chronic encephalitis, hydrocephalus, cerebellar ataxia, arthritis, orchitis, presternal edema, transverse myelitis, Guillain-Barré syndrome, and deafness. 2 Of these, transverse myelitis has been reported as a rare complication of this infection. Previously reported cases of transverse myelitis after mumps infection were complicated with encephalitis, and were more common in younger children. Most of the cases had a slow recovery from the myelitis. 3,4 Here we report a boy who presented with paraparesis and urinary retention due to an LETM as a rare neurological complication after mumps infection. CASE REPORTA 14-year-old boy came to our department with a 3-day history of inability to walk and pain in both legs. He had a history of acute mumps infection 4 weeks prior, for which he had been treated at the pediatric clinic at our hospital. Since mumps infection, he had no other history of infection.Physical examination revealed normal vital signs. There were no systemic signs suggesting acute or subacute mumps infections. The straight-leg raising test readily evoked a radiating pain over the bilateral lower extremities. Neurological examination revealed So Hyun Ahn, et al. Multifocal LETM after Mumps paraparesis during manual motor power examination. Hip flexion/extension and knee flexion/extension were reduced to Medical Research Council (MRC) g...

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“…Whether this merely reflects severe inflammation, or is caused by an autoimmune process and hence representing true ADEM is not clearly known. Unlike postmeasles, varicella, and rubella ADEMs, postmumps encephalomyelitis is not readily distinguishable from more common acute viral encephalitis [62,63].…”

Section: Viral Infectionsmentioning

confidence: 96%

Acute Disseminated Encephalomyelitis: Clinical and Pathogenesis Features

et al. 2008

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Acute disseminated encephalomyelitis (ADEM) is an immune-mediated disorder of the central nervous system (CNS). Disease typically starts with an abrupt onset of neurologic symptoms and signs within days to weeks after a viral infection or immunization. Neuropathological examination of the CNS in ADEM reveals involvement of white matter, with infiltration of monocytoid cells and perivenous demyelination.

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Encephalomyelitis following mumps

Cited by 8 publications

References 11 publications

Magnetic Resonance Imaging Findings of Mumps Meningoencephalitis with Bilateral Hippocampal Lesions without Preceding Acute Parotitis: A Case Report

Magnetic Resonance Imaging Findings of Mumps Meningoencephalitis with Bilateral Hippocampal Lesions without Preceding Acute Parotitis: A Case Report

Multifocal Longitudinally Extensive Transverse Myelitis as a Rare Complication of Mumps Infection

Acute Disseminated Encephalomyelitis: Clinical and Pathogenesis Features

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